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Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway.
Li Q, Guo Y, Ou Q, Cui C, Wu WJ, Tan W, Zhu X, Lanceta LB, Sanganalmath SK, Dawn B, Shinmura K, Rokosh GD, Wang S, Bolli R. Li Q, et al. Among authors: zhu x. Circulation. 2009 Sep 29;120(13):1222-30. doi: 10.1161/CIRCULATIONAHA.108.778688. Epub 2009 Sep 14. Circulation. 2009. PMID: 19752329 Free PMC article.
Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences.
Li Q, Guo Y, Wu WJ, Ou Q, Zhu X, Tan W, Yuan F, Chen N, Dawn B, Luo L, O'Brien E, Bolli R. Li Q, et al. Among authors: zhu x. Basic Res Cardiol. 2011 Nov;106(6):1355-66. doi: 10.1007/s00395-011-0207-7. Epub 2011 Jul 21. Basic Res Cardiol. 2011. PMID: 21779912 Free PMC article.
Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences.
Li Q, Guo Y, Ou Q, Wu WJ, Chen N, Zhu X, Tan W, Yuan F, Dawn B, Luo L, Hunt GN, Bolli R. Li Q, et al. Among authors: zhu x. Basic Res Cardiol. 2011 Nov;106(6):1367-77. doi: 10.1007/s00395-011-0208-6. Epub 2011 Jul 22. Basic Res Cardiol. 2011. PMID: 21785893 Free PMC article.
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