Townsley FM - Search Results

1

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.

Wong TS, Rajagopalan S, Freund SM, Rutherford TJ, Andreeva A, Townsley FM, Petrovich M, Fersht AR. Wong TS, et al. Among authors: townsley fm. Nucleic Acids Res. 2009 Nov;37(20):6765-83. doi: 10.1093/nar/gkp750. Epub 2009 Sep 15. Nucleic Acids Res. 2009. PMID: 19755502 Free PMC article.

2

Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation.

Burge S, Teufel DP, Townsley FM, Freund SM, Bycroft M, Fersht AR. Burge S, et al. Among authors: townsley fm. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3142-7. doi: 10.1073/pnas.0900383106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218448 Free PMC article.

3

Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms.

Rajagopalan S, Sade RS, Townsley FM, Fersht AR. Rajagopalan S, et al. Among authors: townsley fm. Nucleic Acids Res. 2010 Jan;38(3):893-906. doi: 10.1093/nar/gkp1041. Epub 2009 Nov 20. Nucleic Acids Res. 2010. PMID: 19933256 Free PMC article.

4

Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53.

Wong TS, Rajagopalan S, Townsley FM, Freund SM, Petrovich M, Loakes D, Fersht AR. Wong TS, et al. Among authors: townsley fm. Nucleic Acids Res. 2009 Feb;37(2):568-81. doi: 10.1093/nar/gkn974. Epub 2008 Dec 9. Nucleic Acids Res. 2009. PMID: 19066201 Free PMC article.

5

Molecular basis for modulation of the p53 target selectivity by KLF4.

Brandt T, Townsley FM, Teufel DP, Freund SM, Veprintsev DB. Brandt T, et al. Among authors: townsley fm. PLoS One. 2012;7(10):e48252. doi: 10.1371/journal.pone.0048252. Epub 2012 Oct 30. PLoS One. 2012. PMID: 23118962 Free PMC article.

6

The novel p53 isoform "delta p53" is a misfolded protein and does not bind the p21 promoter site.

García-Alai MM, Tidow H, Natan E, Townsley FM, Veprintsev DB, Fersht AR. García-Alai MM, et al. Among authors: townsley fm. Protein Sci. 2008 Oct;17(10):1671-8. doi: 10.1110/ps.036996.108. Epub 2008 Jul 11. Protein Sci. 2008. PMID: 18621913 Free PMC article.

7

Pygopus residues required for its binding to Legless are critical for transcription and development.

Townsley FM, Thompson B, Bienz M. Townsley FM, et al. J Biol Chem. 2004 Feb 13;279(7):5177-83. doi: 10.1074/jbc.M309722200. Epub 2003 Nov 11. J Biol Chem. 2004. PMID: 14612447 Free article.

8

Structural consequences of nucleophosmin mutations in acute myeloid leukemia.

Grummitt CG, Townsley FM, Johnson CM, Warren AJ, Bycroft M. Grummitt CG, et al. Among authors: townsley fm. J Biol Chem. 2008 Aug 22;283(34):23326-32. doi: 10.1074/jbc.M801706200. Epub 2008 May 29. J Biol Chem. 2008. PMID: 18511415 Free PMC article.

9

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

Townsley FM, Wilson DW, Pelham HR. Townsley FM, et al. EMBO J. 1993 Jul;12(7):2821-9. doi: 10.1002/j.1460-2075.1993.tb05943.x. EMBO J. 1993. PMID: 8392934 Free PMC article.

10

The APC tumour suppressor has a nuclear export function.

Rosin-Arbesfeld R, Townsley F, Bienz M. Rosin-Arbesfeld R, et al. Nature. 2000 Aug 31;406(6799):1009-12. doi: 10.1038/35023016. Nature. 2000. PMID: 10984057

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