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Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Malamas MS, Barnes K, Hui Y, Johnson M, Lovering F, Condon J, Fobare W, Solvibile W, Turner J, Hu Y, Manas ES, Fan K, Olland A, Chopra R, Bard J, Pangalos MN, Reinhart P, Robichaud AJ. Malamas MS, et al. Among authors: hui y. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2068-73. doi: 10.1016/j.bmcl.2010.02.075. Epub 2010 Feb 23. Bioorg Med Chem Lett. 2010. PMID: 20223661
Heterobiaryl purine derivatives as potent antiproliferative agents: inhibitors of cyclin dependent kinases. Part II.
Trova MP, Barnes KD, Alicea L, Benanti T, Bielaska M, Bilotta J, Bliss B, Duong TN, Haydar S, Herr RJ, Hui Y, Johnson M, Lehman JM, Peace D, Rainka M, Snider P, Salamone S, Tregay S, Zheng X, Friedrich TD. Trova MP, et al. Among authors: hui y. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6613-7. doi: 10.1016/j.bmcl.2009.10.011. Epub 2009 Oct 12. Bioorg Med Chem Lett. 2009. PMID: 19854650
Piperidinyl-2-phenethylamino inhibitors of DPP-IV for the treatment of type 2 diabetes.
Benbow JW, Andrews KA, Aubrecht J, Beebe D, Boyer D, Doran S, Homiski M, Hui Y, McPherson K, Parker JC, Treadway J, Vanvolkenberg M, Zembrowski WJ. Benbow JW, et al. Among authors: hui y. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2220-3. doi: 10.1016/j.bmcl.2009.02.099. Epub 2009 Feb 28. Bioorg Med Chem Lett. 2009. PMID: 19285862
1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes.
Andrews KM, Beebe DA, Benbow JW, Boyer DA, Doran SD, Hui Y, Liu S, McPherson RK, Neagu C, Parker JC, Piotrowski DW, Schneider SR, Treadway JL, VanVolkenberg MA, Zembrowski WJ. Andrews KM, et al. Among authors: hui y. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1810-4. doi: 10.1016/j.bmcl.2011.01.055. Epub 2011 Jan 31. Bioorg Med Chem Lett. 2011. PMID: 21324688
1,376 results