Muegge I - Search Results

1

Design and synthesis of substituted nicotinamides as inhibitors of soluble epoxide hydrolase.

Taylor SJ, Soleymanzadeh F, Eldrup AB, Farrow NA, Muegge I, Kukulka A, Kabcenell AK, De Lombaert S. Taylor SJ, et al. Among authors: muegge i. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5864-8. doi: 10.1016/j.bmcl.2009.08.074. Epub 2009 Aug 26. Bioorg Med Chem Lett. 2009. PMID: 19758802

2

Virtual screening for kinase targets.

Muegge I, Enyedy IJ. Muegge I, et al. Curr Med Chem. 2004 Mar;11(6):693-707. doi: 10.2174/0929867043455684. Curr Med Chem. 2004. PMID: 15032724 Review.

3

Substituted indanylacetic acids as PPAR-alpha-gamma activators.

Lowe DB, Bifulco N, Bullock WH, Claus T, Coish P, Dai M, Dela Cruz FE, Dickson D, Fan D, Hoover-Litty H, Li T, Ma X, Mannelly G, Monahan MK, Muegge I, O'Connor S, Rodriguez M, Shelekhin T, Stolle A, Sweet L, Wang M, Wang Y, Zhang C, Zhang HJ, Zhang M, Zhao K, Zhao Q, Zhu J, Zhu L, Tsutsumi M. Lowe DB, et al. Among authors: muegge i. Bioorg Med Chem Lett. 2006 Jan 15;16(2):297-301. doi: 10.1016/j.bmcl.2005.10.008. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275080

4

Scaffold hopping through virtual screening using 2D and 3D similarity descriptors: ranking, voting, and consensus scoring.

Zhang Q, Muegge I. Zhang Q, et al. Among authors: muegge i. J Med Chem. 2006 Mar 9;49(5):1536-48. doi: 10.1021/jm050468i. J Med Chem. 2006. PMID: 16509572

5

PMF scoring revisited.

Muegge I. Muegge I. J Med Chem. 2006 Oct 5;49(20):5895-902. doi: 10.1021/jm050038s. J Med Chem. 2006. PMID: 17004705

6

Synergies of virtual screening approaches.

Muegge I. Muegge I. Mini Rev Med Chem. 2008 Aug;8(9):927-33. doi: 10.2174/138955708785132792. Mini Rev Med Chem. 2008. PMID: 18691150 Review.

7

Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase.

Eldrup AB, Soleymanzadeh F, Taylor SJ, Muegge I, Farrow NA, Joseph D, McKellop K, Man CC, Kukulka A, De Lombaert S. Eldrup AB, et al. Among authors: muegge i. J Med Chem. 2009 Oct 8;52(19):5880-95. doi: 10.1021/jm9005302. J Med Chem. 2009. PMID: 19746975

8

Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method.

Kowalski JA, Swinamer AD, Muegge I, Eldrup AB, Kukulka A, Cywin CL, De Lombaert S. Kowalski JA, et al. Among authors: muegge i. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3703-7. doi: 10.1016/j.bmcl.2010.04.078. Epub 2010 Apr 22. Bioorg Med Chem Lett. 2010. PMID: 20472432

9

Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13.

Taylor SJ, Abeywardane A, Liang S, Muegge I, Padyana AK, Xiong Z, Hill-Drzewi M, Farmer B, Li X, Collins B, Li JX, Heim-Riether A, Proudfoot J, Zhang Q, Goldberg D, Zuvela-Jelaska L, Zaher H, Li J, Farrow NA. Taylor SJ, et al. Among authors: muegge i. J Med Chem. 2011 Dec 8;54(23):8174-87. doi: 10.1021/jm201129m. Epub 2011 Nov 9. J Med Chem. 2011. PMID: 22017539

10

Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists.

Taylor SJ, Soleymanzadeh F, Muegge I, Akiba I, Taki N, Ueda S, Mainolfi E, Eldrup AB. Taylor SJ, et al. Among authors: muegge i. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2177-80. doi: 10.1016/j.bmcl.2013.01.105. Epub 2013 Feb 4. Bioorg Med Chem Lett. 2013. PMID: 23453841

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