Belardinelli L - Search Results

1

LQTS mutation N1325S in cardiac sodium channel gene SCN5A causes cardiomyocyte apoptosis, cardiac fibrosis and contractile dysfunction in mice.

Zhang T, Yong SL, Drinko JK, Popović ZB, Shryock JC, Belardinelli L, Wang QK. Zhang T, et al. Among authors: belardinelli l. Int J Cardiol. 2011 Mar 3;147(2):239-45. doi: 10.1016/j.ijcard.2009.08.047. Epub 2009 Sep 17. Int J Cardiol. 2011. PMID: 19762097 Free PMC article.

2

Late sodium current inhibition as a new cardioprotective approach.

Hale SL, Shryock JC, Belardinelli L, Sweeney M, Kloner RA. Hale SL, et al. Among authors: belardinelli l. J Mol Cell Cardiol. 2008 Jun;44(6):954-967. doi: 10.1016/j.yjmcc.2008.03.019. Epub 2008 Apr 8. J Mol Cell Cardiol. 2008. PMID: 18462746 Review.

3

Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.

Song Y, Shryock JC, Wagner S, Maier LS, Belardinelli L. Song Y, et al. Among authors: belardinelli l. J Pharmacol Exp Ther. 2006 Jul;318(1):214-22. doi: 10.1124/jpet.106.101832. Epub 2006 Mar 24. J Pharmacol Exp Ther. 2006. PMID: 16565163

4

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice.

Yao L, Fan P, Jiang Z, Viatchenko-Karpinski S, Wu Y, Kornyeyev D, Hirakawa R, Budas GR, Rajamani S, Shryock JC, Belardinelli L. Yao L, et al. Among authors: belardinelli l. Am J Physiol Cell Physiol. 2011 Sep;301(3):C577-86. doi: 10.1152/ajpcell.00125.2011. Epub 2011 Jun 15. Am J Physiol Cell Physiol. 2011. PMID: 21677263 Free article.

5

The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.

Shryock JC, Song Y, Rajamani S, Antzelevitch C, Belardinelli L. Shryock JC, et al. Among authors: belardinelli l. Cardiovasc Res. 2013 Sep 1;99(4):600-11. doi: 10.1093/cvr/cvt145. Epub 2013 Jun 10. Cardiovasc Res. 2013. PMID: 23752976 Free PMC article. Review.

6

Cardiac late Na⁺ current: proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress.

Belardinelli L, Giles WR, Rajamani S, Karagueuzian HS, Shryock JC. Belardinelli L, et al. Heart Rhythm. 2015 Feb;12(2):440-8. doi: 10.1016/j.hrthm.2014.11.009. Epub 2014 Nov 11. Heart Rhythm. 2015. PMID: 25460862 Review.

7

Inhibition of late sodium current to reduce electrical and mechanical dysfunction of ischaemic myocardium.

Shryock JC, Belardinelli L. Shryock JC, et al. Among authors: belardinelli l. Br J Pharmacol. 2008 Mar;153(6):1128-32. doi: 10.1038/sj.bjp.0707522. Epub 2007 Dec 10. Br J Pharmacol. 2008. PMID: 18071302 Free PMC article.

8

Intracellular Na+ overload causes oxidation of CaMKII and leads to Ca2+ mishandling in isolated ventricular myocytes.

Viatchenko-Karpinski S, Kornyeyev D, El-Bizri N, Budas G, Fan P, Jiang Z, Yang J, Anderson ME, Shryock JC, Chang CP, Belardinelli L, Yao L. Viatchenko-Karpinski S, et al. Among authors: belardinelli l. J Mol Cell Cardiol. 2014 Nov;76:247-56. doi: 10.1016/j.yjmcc.2014.09.009. Epub 2014 Sep 22. J Mol Cell Cardiol. 2014. PMID: 25252177 Free PMC article.

9

The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-L-carnitine to increase late INa and cause ventricular diastolic dysfunction.

Wu Y, Song Y, Belardinelli L, Shryock JC. Wu Y, et al. Among authors: belardinelli l. J Pharmacol Exp Ther. 2009 Aug;330(2):550-7. doi: 10.1124/jpet.109.151936. Epub 2009 Apr 29. J Pharmacol Exp Ther. 2009. PMID: 19403851

10

An increase in late sodium current potentiates the proarrhythmic activities of low-risk QT-prolonging drugs in female rabbit hearts.

Wu L, Shryock JC, Song Y, Belardinelli L. Wu L, et al. Among authors: belardinelli l. J Pharmacol Exp Ther. 2006 Feb;316(2):718-26. doi: 10.1124/jpet.105.094862. Epub 2005 Oct 18. J Pharmacol Exp Ther. 2006. PMID: 16234410

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