Chou CJ - Search Results

1

Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing.

Xu C, Soragni E, Chou CJ, Herman D, Plasterer HL, Rusche JR, Gottesfeld JM. Xu C, et al. Among authors: chou cj. Chem Biol. 2009 Sep 25;16(9):980-9. doi: 10.1016/j.chembiol.2009.07.010. Chem Biol. 2009. PMID: 19778726 Free PMC article.

2

Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases.

Chou CJ, Herman D, Gottesfeld JM. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9. doi: 10.1074/jbc.M807045200. Epub 2008 Oct 24. J Biol Chem. 2008. PMID: 18953021 Free PMC article.

3

Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors.

Hu F, Chou CJ, Gottesfeld JM. Hu F, et al. Among authors: chou cj. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3928-31. doi: 10.1016/j.bmcl.2009.03.085. Epub 2009 Mar 25. Bioorg Med Chem Lett. 2009. PMID: 19362838 Free PMC article.

4

Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia.

Soragni E, Chou CJ, Rusche JR, Gottesfeld JM. Soragni E, et al. Among authors: chou cj. Front Neurol. 2015 Mar 5;6:44. doi: 10.3389/fneur.2015.00044. eCollection 2015. Front Neurol. 2015. PMID: 25798128 Free PMC article.

5

Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.

Chou CJ, Farkas ME, Tsai SM, Alvarez D, Dervan PB, Gottesfeld JM. Chou CJ, et al. Mol Cancer Ther. 2008 Apr;7(4):769-78. doi: 10.1158/1535-7163.MCT-08-0130. Mol Cancer Ther. 2008. PMID: 18413791 Free PMC article.

6

Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.

Rai M, Soragni E, Chou CJ, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pandolfo M. Rai M, et al. Among authors: chou cj. PLoS One. 2010 Jan 21;5(1):e8825. doi: 10.1371/journal.pone.0008825. PLoS One. 2010. PMID: 20098685 Free PMC article.

7

A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate.

Alvarez D, Chou CJ, Latella L, Zeitlin SG, Ku S, Puri PL, Dervan PB, Gottesfeld JM. Alvarez D, et al. Among authors: chou cj. Cell Cycle. 2006 Jul;5(14):1537-48. doi: 10.4161/cc.5.14.2913. Epub 2006 Jul 17. Cell Cycle. 2006. PMID: 16861886

8

Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate.

Chou CJ, O'Hare T, Lefebvre S, Alvarez D, Tyner JW, Eide CA, Druker BJ, Gottesfeld JM. Chou CJ, et al. PLoS One. 2008;3(10):e3593. doi: 10.1371/journal.pone.0003593. Epub 2008 Oct 31. PLoS One. 2008. PMID: 18974832 Free PMC article.

9

Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.

Tsai SM, Farkas ME, Chou CJ, Gottesfeld JM, Dervan PB. Tsai SM, et al. Among authors: chou cj. Nucleic Acids Res. 2007;35(1):307-16. doi: 10.1093/nar/gkl1025. Epub 2006 Dec 14. Nucleic Acids Res. 2007. PMID: 17170006 Free PMC article.

10

Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors.

Zhao C, Zang J, Ding Q, Inks ES, Xu W, Chou CJ, Zhang Y. Zhao C, et al. Among authors: chou cj. Eur J Med Chem. 2018 Apr 25;150:282-291. doi: 10.1016/j.ejmech.2018.03.002. Epub 2018 Mar 6. Eur J Med Chem. 2018. PMID: 29533873

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