Floquet N - Search Results

1

Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).

Floquet N, M'Kadmi C, Perahia D, Gagne D, Bergé G, Marie J, Banères JL, Galleyrand JC, Fehrentz JA, Martinez J. Floquet N, et al. J Mol Biol. 2010 Jan 29;395(4):769-84. doi: 10.1016/j.jmb.2009.09.051. Epub 2009 Sep 25. J Mol Biol. 2010. PMID: 19782690

2

Normal mode analysis as a prerequisite for drug design: application to matrix metalloproteinases inhibitors.

Floquet N, Marechal JD, Badet-Denisot MA, Robert CH, Dauchez M, Perahia D. Floquet N, et al. FEBS Lett. 2006 Oct 2;580(22):5130-6. doi: 10.1016/j.febslet.2006.08.037. Epub 2006 Sep 1. FEBS Lett. 2006. PMID: 16962102 Free article.

3

Human thrombospondin's (TSP-1) C-terminal domain opens to interact with the CD-47 receptor: a molecular modeling study.

Floquet N, Dedieu S, Martiny L, Dauchez M, Perahia D. Floquet N, et al. Arch Biochem Biophys. 2008 Oct 1;478(1):103-9. doi: 10.1016/j.abb.2008.07.015. Epub 2008 Jul 23. Arch Biochem Biophys. 2008. PMID: 18675774

4

Collective motions in glucosamine-6-phosphate synthase: influence of ligand binding and role in ammonia channelling and opening of the fructose-6-phosphate binding site.

Floquet N, Durand P, Maigret B, Badet B, Badet-Denisot MA, Perahia D. Floquet N, et al. J Mol Biol. 2009 Jan 16;385(2):653-64. doi: 10.1016/j.jmb.2008.10.032. Epub 2008 Oct 19. J Mol Biol. 2009. PMID: 18976669

5

Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a.

Gozé C, Bergé G, M'Kadmi C, Floquet N, Gagne D, Galleyrand JC, Fehrentz JA, Martinez J. Gozé C, et al. Among authors: floquet n. Eur J Pharmacol. 2010 Sep 25;643(2-3):153-61. doi: 10.1016/j.ejphar.2010.06.018. Epub 2010 Jun 30. Eur J Pharmacol. 2010. PMID: 20599926

6

L-arginine binding to human inducible nitric oxide synthase: an antisymmetric funnel route toward isoform-specific inhibitors?

Floquet N, Hernandez JF, Boucher JL, Martinez J. Floquet N, et al. J Chem Inf Model. 2011 Jun 27;51(6):1325-35. doi: 10.1021/ci100422v. Epub 2011 May 16. J Chem Inf Model. 2011. PMID: 21574590

7

A concerted mechanism for opening the GDP binding pocket and release of the nucleotide in hetero-trimeric G-proteins.

Louet M, Perahia D, Martinez J, Floquet N. Louet M, et al. Among authors: floquet n. J Mol Biol. 2011 Aug 5;411(1):298-312. doi: 10.1016/j.jmb.2011.05.034. Epub 2011 May 30. J Mol Biol. 2011. PMID: 21663745

8

Chemical optimization of new ligands of the low-density lipoprotein receptor as potential vectors for central nervous system targeting.

Malcor JD, Payrot N, David M, Faucon A, Abouzid K, Jacquot G, Floquet N, Debarbieux F, Rougon G, Martinez J, Khrestchatisky M, Vlieghe P, Lisowski V. Malcor JD, et al. Among authors: floquet n. J Med Chem. 2012 Mar 8;55(5):2227-41. doi: 10.1021/jm2014919. Epub 2012 Feb 14. J Med Chem. 2012. PMID: 22257077

9

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor.

Mary S, Damian M, Louet M, Floquet N, Fehrentz JA, Marie J, Martinez J, Banères JL. Mary S, et al. Among authors: floquet n. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8304-9. doi: 10.1073/pnas.1119881109. Epub 2012 May 9. Proc Natl Acad Sci U S A. 2012. PMID: 22573814 Free PMC article.

10

GDP release preferentially occurs on the phosphate side in heterotrimeric G-proteins.

Louet M, Martinez J, Floquet N. Louet M, et al. Among authors: floquet n. PLoS Comput Biol. 2012;8(7):e1002595. doi: 10.1371/journal.pcbi.1002595. Epub 2012 Jul 19. PLoS Comput Biol. 2012. PMID: 22829757 Free PMC article.

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