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Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).
Floquet N, M'Kadmi C, Perahia D, Gagne D, Bergé G, Marie J, Banères JL, Galleyrand JC, Fehrentz JA, Martinez J. Floquet N, et al. Among authors: galleyrand jc. J Mol Biol. 2010 Jan 29;395(4):769-84. doi: 10.1016/j.jmb.2009.09.051. Epub 2009 Sep 25. J Mol Biol. 2010. PMID: 19782690
Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.
Moulin A, Demange L, Bergé G, Gagne D, Ryan J, Mousseaux D, Heitz A, Perrissoud D, Locatelli V, Torsello A, Galleyrand JC, Fehrentz JA, Martinez J. Moulin A, et al. Among authors: galleyrand jc. J Med Chem. 2007 Nov 15;50(23):5790-806. doi: 10.1021/jm0704550. Epub 2007 Oct 10. J Med Chem. 2007. PMID: 17927165
New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations.
Moulin A, Demange L, Ryan J, Mousseaux D, Sanchez P, Bergé G, Gagne D, Perrissoud D, Locatelli V, Torsello A, Galleyrand JC, Fehrentz JA, Martinez J. Moulin A, et al. Among authors: galleyrand jc. J Med Chem. 2008 Feb 14;51(3):689-93. doi: 10.1021/jm701292s. Epub 2008 Jan 15. J Med Chem. 2008. PMID: 18193826
Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.
Leyris JP, Roux T, Trinquet E, Verdié P, Fehrentz JA, Oueslati N, Douzon S, Bourrier E, Lamarque L, Gagne D, Galleyrand JC, M'kadmi C, Martinez J, Mary S, Banères JL, Marie J. Leyris JP, et al. Among authors: galleyrand jc. Anal Biochem. 2011 Jan 15;408(2):253-62. doi: 10.1016/j.ab.2010.09.030. Epub 2010 Sep 24. Anal Biochem. 2011. PMID: 20937574
34 results