Martinez J - Search Results

1

Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).

Floquet N, M'Kadmi C, Perahia D, Gagne D, Bergé G, Marie J, Banères JL, Galleyrand JC, Fehrentz JA, Martinez J. Floquet N, et al. Among authors: martinez j. J Mol Biol. 2010 Jan 29;395(4):769-84. doi: 10.1016/j.jmb.2009.09.051. Epub 2009 Sep 25. J Mol Biol. 2010. PMID: 19782690

2

Recent developments in ghrelin receptor ligands.

Moulin A, Ryan J, Martinez J, Fehrentz JA. Moulin A, et al. Among authors: martinez j. ChemMedChem. 2007 Sep;2(9):1242-59. doi: 10.1002/cmdc.200700015. ChemMedChem. 2007. PMID: 17520591 Review.

3

Trisubstituted 1,2,4-triazoles as ligands for the ghrelin receptor: on the significance of the orientation and substitution at position 3.

Moulin A, Demange L, Ryan J, M'Kadmi C, Galleyrand JC, Martinez J, Fehrentz JA. Moulin A, et al. Among authors: martinez j. Bioorg Med Chem Lett. 2008 Jan 1;18(1):164-8. doi: 10.1016/j.bmcl.2007.10.113. Epub 2007 Nov 4. Bioorg Med Chem Lett. 2008. PMID: 18023181

4

Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a.

Gozé C, Bergé G, M'Kadmi C, Floquet N, Gagne D, Galleyrand JC, Fehrentz JA, Martinez J. Gozé C, et al. Among authors: martinez j. Eur J Pharmacol. 2010 Sep 25;643(2-3):153-61. doi: 10.1016/j.ejphar.2010.06.018. Epub 2010 Jun 30. Eur J Pharmacol. 2010. PMID: 20599926

5

A concerted mechanism for opening the GDP binding pocket and release of the nucleotide in hetero-trimeric G-proteins.

Louet M, Perahia D, Martinez J, Floquet N. Louet M, et al. Among authors: martinez j. J Mol Biol. 2011 Aug 5;411(1):298-312. doi: 10.1016/j.jmb.2011.05.034. Epub 2011 May 30. J Mol Biol. 2011. PMID: 21663745

6

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor.

Mary S, Damian M, Louet M, Floquet N, Fehrentz JA, Marie J, Martinez J, Banères JL. Mary S, et al. Among authors: martinez j. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8304-9. doi: 10.1073/pnas.1119881109. Epub 2012 May 9. Proc Natl Acad Sci U S A. 2012. PMID: 22573814 Free PMC article.

7

How ligands and signalling proteins affect G-protein-coupled receptors' conformational landscape.

Mary S, Fehrentz JA, Damian M, Verdié P, Martinez J, Marie J, Banères JL. Mary S, et al. Among authors: martinez j. Biochem Soc Trans. 2013 Feb 1;41(1):144-7. doi: 10.1042/BST20120267. Biochem Soc Trans. 2013. PMID: 23356274 Review.

8

Conformational restriction of G-proteins Coupled Receptors (GPCRs) upon complexation to G-proteins: a putative activation mode of GPCRs?

Louet M, Karakas E, Perret A, Perahia D, Martinez J, Floquet N. Louet M, et al. Among authors: martinez j. FEBS Lett. 2013 Aug 19;587(16):2656-61. doi: 10.1016/j.febslet.2013.06.052. Epub 2013 Jul 10. FEBS Lett. 2013. PMID: 23851072 Free article.

9

Fundamentals of modern peptide synthesis.

Amblard M, Fehrentz JA, Martinez J, Subra G. Amblard M, et al. Among authors: martinez j. Methods Mol Biol. 2005;298:3-24. doi: 10.1385/1-59259-877-3:003. Methods Mol Biol. 2005. PMID: 15897611

10

Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway.

Mousseaux D, Le Gallic L, Ryan J, Oiry C, Gagne D, Fehrentz JA, Galleyrand JC, Martinez J. Mousseaux D, et al. Among authors: martinez j. Br J Pharmacol. 2006 Jun;148(3):350-65. doi: 10.1038/sj.bjp.0706727. Br J Pharmacol. 2006. PMID: 16582936 Free PMC article.

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