Kim HM - Search Results

1

A novel gamma-lactam-based histone deacetylase inhibitor potently inhibits the growth of human breast and renal cancer cells.

Kwon HK, Ahn SH, Park SH, Park JH, Park JW, Kim HM, Park SK, Lee K, Lee CW, Choi E, Han G, Han JW. Kwon HK, et al. Among authors: kim hm. Biol Pharm Bull. 2009 Oct;32(10):1723-7. doi: 10.1248/bpb.32.1723. Biol Pharm Bull. 2009. PMID: 19801834 Free article.

2

Synthesis, enzymatic inhibition, and cancer cell growth inhibition of novel delta-lactam-based histone deacetylase (HDAC) inhibitors.

Kim HM, Lee K, Park BW, Ryu DK, Kim K, Lee CW, Park SK, Han JW, Lee HY, Lee HY, Han G. Kim HM, et al. Among authors: kim k. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4068-70. doi: 10.1016/j.bmcl.2006.04.091. Epub 2006 May 24. Bioorg Med Chem Lett. 2006. PMID: 16723227

3

Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors.

Kim HM, Hong SH, Kim MS, Lee CW, Kang JS, Lee K, Park SK, Han JW, Lee HY, Choi Y, Kwon HJ, Han G. Kim HM, et al. Among authors: kim ms. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6234-8. doi: 10.1016/j.bmcl.2007.09.034. Epub 2007 Sep 11. Bioorg Med Chem Lett. 2007. PMID: 17904843

4

A novel delta-lactam-based histone deacetylase inhibitor, KBH-A42, induces cell cycle arrest and apoptosis in colon cancer cells.

Kang MR, Kang JS, Han SB, Kim JH, Kim DM, Lee K, Lee CW, Lee KH, Lee CH, Han G, Kang JS, Kim HM, Park SK. Kang MR, et al. Among authors: kim hm, kim dm, kim jh. Biochem Pharmacol. 2009 Sep 1;78(5):486-94. doi: 10.1016/j.bcp.2009.05.010. Epub 2009 May 13. Biochem Pharmacol. 2009. PMID: 19445901

5

Discovery of pyridone-based histone deacetylase inhibitors: approaches for metabolic stability.

Cho M, Choi E, Yang JS, Lee C, Seo JJ, Kim BS, Oh SJ, Kim HM, Lee K, Park SK, Kwon HJ, Han G. Cho M, et al. Among authors: kim bs, kim hm. ChemMedChem. 2013 Feb;8(2):272-9. doi: 10.1002/cmdc.201200529. Epub 2013 Jan 4. ChemMedChem. 2013. PMID: 23292995

6

A248, a novel synthetic HDAC inhibitor, induces apoptosis through the inhibition of specificity protein 1 and its downstream proteins in human prostate cancer cells.

Choi ES, Han G, Park SK, Lee K, Kim HJ, Cho SD, Kim HM. Choi ES, et al. Among authors: kim hj, kim hm. Mol Med Rep. 2013 Jul;8(1):195-200. doi: 10.3892/mmr.2013.1481. Epub 2013 May 16. Mol Med Rep. 2013. PMID: 23685644

7

Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors: part II.

Lee C, Choi E, Cho M, Lee B, Oh SJ, Park SK, Lee K, Kim HM, Han G. Lee C, et al. Among authors: kim hm. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4189-92. doi: 10.1016/j.bmcl.2012.04.045. Epub 2012 Apr 21. Bioorg Med Chem Lett. 2012. PMID: 22578459

8

Chemopreventive and chemotherapeutic effect of a novel histone deacetylase inhibitor, by specificity protein 1 in MDA-MB-231 human breast cancer cells.

Shin JA, Han G, Kim HJ, Kim HM, Cho SD. Shin JA, et al. Among authors: kim hj, kim hm. Eur J Cancer Prev. 2014 Jul;23(4):277-85. doi: 10.1097/CEJ.0000000000000041. Eur J Cancer Prev. 2014. PMID: 24871559

9

Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.

Kim HM, Ryu DK, Choi Y, Park BW, Lee K, Han SB, Lee CW, Kang MR, Kang JS, Boovanahalli SK, Park SK, Han JW, Chun TG, Lee HY, Nam KY, Choi EH, Han G. Kim HM, et al. J Med Chem. 2007 May 31;50(11):2737-41. doi: 10.1021/jm0613828. Epub 2007 May 4. J Med Chem. 2007. PMID: 17477518

10

Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model.

Choi Y, Park SK, Kim HM, Kang JS, Yoon YD, Han SB, Han JW, Yang JS, Han G. Choi Y, et al. Among authors: kim hm. Exp Mol Med. 2008 Oct 31;40(5):574-81. doi: 10.3858/emm.2008.40.5.574. Exp Mol Med. 2008. PMID: 18985016 Free PMC article.

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