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Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum.
Popoli P, Pintor A, Domenici MR, Frank C, Tebano MT, Pèzzola A, Scarchilli L, Quarta D, Reggio R, Malchiodi-Albedi F, Falchi M, Massotti M. Popoli P, et al. Among authors: pezzola a. J Neurosci. 2002 Mar 1;22(5):1967-75. doi: 10.1523/JNEUROSCI.22-05-01967.2002. J Neurosci. 2002. PMID: 11880527 Free PMC article.
Chronic treatment with the mGlu5R antagonist MPEP reduces the functional effects of the mGlu5R agonist CHPG in the striatum of 6-hydroxydopamine-lesioned rats: possible relevance to the effects of mGlu5R blockade in Parkinson's disease.
Domenici MR, Potenza RL, Martire A, Coccurello R, Pèzzola A, Reggio R, Tebano MT, Popoli P. Domenici MR, et al. Among authors: pezzola a. J Neurosci Res. 2005 Jun 1;80(5):646-54. doi: 10.1002/jnr.20489. J Neurosci Res. 2005. PMID: 15880742
Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration.
Minghetti L, Greco A, Potenza RL, Pezzola A, Blum D, Bantubungi K, Popoli P. Minghetti L, et al. Among authors: pezzola a. J Neuropathol Exp Neurol. 2007 May;66(5):363-71. doi: 10.1097/nen.0b013e3180517477. J Neuropathol Exp Neurol. 2007. PMID: 17483693
Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.
Domenici MR, Chiodi V, Averna M, Armida M, Pèzzola A, Pepponi R, Ferrante A, Bader M, Fuxe K, Popoli P. Domenici MR, et al. Among authors: pezzola a. Purinergic Signal. 2018 Sep;14(3):235-243. doi: 10.1007/s11302-018-9609-4. Epub 2018 May 16. Purinergic Signal. 2018. PMID: 29770921 Free PMC article.
72 results