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211 results

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Page 1
A genomic screen identifies TYRO3 as a MITF regulator in melanoma.
Zhu S, Wurdak H, Wang Y, Galkin A, Tao H, Li J, Lyssiotis CA, Yan F, Tu BP, Miraglia L, Walker J, Sun F, Orth A, Schultz PG, Wu X. Zhu S, et al. Among authors: lyssiotis ca. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17025-30. doi: 10.1073/pnas.0909292106. Epub 2009 Sep 23. Proc Natl Acad Sci U S A. 2009. PMID: 19805117 Free PMC article.
A small molecule primes embryonic stem cells for differentiation.
Zhu S, Wurdak H, Wang J, Lyssiotis CA, Peters EC, Cho CY, Wu X, Schultz PG. Zhu S, et al. Among authors: lyssiotis ca. Cell Stem Cell. 2009 May 8;4(5):416-26. doi: 10.1016/j.stem.2009.04.001. Cell Stem Cell. 2009. PMID: 19427291 Free article.
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, Jaenisch R. Lyssiotis CA, et al. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8912-7. doi: 10.1073/pnas.0903860106. Epub 2009 May 15. Proc Natl Acad Sci U S A. 2009. PMID: 19447925 Free PMC article.
Chemical control of stem cell fate and developmental potential.
Lyssiotis CA, Lairson LL, Boitano AE, Wurdak H, Zhu S, Schultz PG. Lyssiotis CA, et al. Angew Chem Int Ed Engl. 2011 Jan 3;50(1):200-42. doi: 10.1002/anie.201004284. Angew Chem Int Ed Engl. 2011. PMID: 21184400 Review.
Small molecule-based approaches to adult stem cell therapies.
Lairson LL, Lyssiotis CA, Zhu S, Schultz PG. Lairson LL, et al. Among authors: lyssiotis ca. Annu Rev Pharmacol Toxicol. 2013;53:107-25. doi: 10.1146/annurev-pharmtox-011112-140300. Annu Rev Pharmacol Toxicol. 2013. PMID: 23294307 Review.
A regenerative approach to the treatment of multiple sclerosis.
Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL. Deshmukh VA, et al. Among authors: lyssiotis ca. Nature. 2013 Oct 17;502(7471):327-332. doi: 10.1038/nature12647. Epub 2013 Oct 9. Nature. 2013. PMID: 24107995 Free PMC article.
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Mullarky E, Lucki NC, Beheshti Zavareh R, Anglin JL, Gomes AP, Nicolay BN, Wong JC, Christen S, Takahashi H, Singh PK, Blenis J, Warren JD, Fendt SM, Asara JM, DeNicola GM, Lyssiotis CA, Lairson LL, Cantley LC. Mullarky E, et al. Among authors: lyssiotis ca. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83. doi: 10.1073/pnas.1521548113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831078 Free PMC article.
A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers.
Bollong MJ, Pietilä M, Pearson AD, Sarkar TR, Ahmad I, Soundararajan R, Lyssiotis CA, Mani SA, Schultz PG, Lairson LL. Bollong MJ, et al. Among authors: lyssiotis ca. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E9912. doi: 10.1073/pnas.1716009114. Epub 2017 Oct 30. Proc Natl Acad Sci U S A. 2017. PMID: 29087350 Free PMC article.
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, Jaenisch R, Schultz PG. Staerk J, et al. Among authors: lyssiotis ca. Angew Chem Int Ed Engl. 2011 Jun 14;50(25):5734-6. doi: 10.1002/anie.201101042. Epub 2011 May 5. Angew Chem Int Ed Engl. 2011. PMID: 21547985 Free PMC article. No abstract available.
211 results