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Disability in ecology and evolution.
Hutchinson JR, Rabosky DL. Hutchinson JR, et al. Trends Ecol Evol. 2024 Dec 19:S0169-5347(24)00283-0. doi: 10.1016/j.tree.2024.11.010. Online ahead of print. Trends Ecol Evol. 2024. PMID: 39706730 No abstract available.
Proteolytic shedding of CD46 from human hepatocytes indicates liver stress.
Kupke P, Yang Zhou J, Glehr G, Riquelme P, Scheibert L, Adenugba A, Schlitt HJ, Geissler EK, Werner JM, Hutchinson JA. Kupke P, et al. Among authors: hutchinson ja. Heliyon. 2024 Nov 30;10(23):e40841. doi: 10.1016/j.heliyon.2024.e40841. eCollection 2024 Dec 15. Heliyon. 2024. PMID: 39698100 Free PMC article.
Stratified Medicine Paediatrics: Cell free DNA and serial tumour sequencing identifies subtype specific cancer evolution and epigenetic states.
George SL, Lynn C, Stankunaite R, Hughes D, Sauer CM, Chalker J, Waqar Ahmed S, Oostveen M, Proszek PZ, Yuan L, Shaikh R, Jamal S, Brew A, Tall J, Rogers T, Clifford SC, Vormoor J, Shipley JM, Tweddle DA, Jones C, Willis C, Burke GAA, Vedi A, Howell L, Johnston R, Rees H, Adams M, Jesudason A, Ronghe M, Elliott M, Ross E, Makin G, Campbell-Hewson Q, Grundy RG, Turnbull J, Wilson S, Lee V, Gray JC, Stoneham S, Gatz SA, Marshall LV, Angelini P, Anderson J, Cresswell GD, Graham TA, Al-Lazikani B, Cortes-Ciriano I, Kearns P, Hutchinson JC, Hargrave D, Jacques TS, Hubank M, Sottoriva A, Chesler L. George SL, et al. Among authors: hutchinson jc. Cancer Discov. 2024 Dec 19. doi: 10.1158/2159-8290.CD-24-0916. Online ahead of print. Cancer Discov. 2024. PMID: 39693475
Optimization of Potent and Selective Cyclohexyl Acid ERAP1 Inhibitors Using Structure- and Property-Based Drug Design.
Hryczanek RP, Hackett AS, Rowland P, Chung CW, Convery MA, Holmes DS, Hutchinson JP, Kitchen S, Korczynska J, Law RP, Lea JD, Liddle J, Lonsdale R, Neu M, Nickels L, Phillipou A, Rowedder JE, Schneck JL, Scott-Stevens P, Sheehan H, Tayler CL, Temponeras I, Tinworth CP, Walker AL, Wojno-Picon J, Young RJ, Lindsay DM, Stratikos E. Hryczanek RP, et al. Among authors: hutchinson jp. ACS Med Chem Lett. 2024 Nov 6;15(12):2107-2114. doi: 10.1021/acsmedchemlett.4c00401. eCollection 2024 Dec 12. ACS Med Chem Lett. 2024. PMID: 39691536 Free PMC article.
Predisposition footprints in the somatic genome of Wilms tumours.
Treger TD, Wegert J, Wenger A, Coorens THH, Al-Saadi R, Kemps PG, Kennedy J, Parks C, Anderson ND, Hodder A, Letunovska A, Jung H, Ogbonnah T, Trinh MK, Lee-Six H, Morcrette G, van den Heuvel-Eibrink MM, Drost J, van Boxtel R, Bertrums EJM, Goemans BF, Antoniou E, Reinhardt D, Streitenberger H, Ziegler B, Bartram J, Hutchinson JC, Vujanic GM, Vokuhl C, Chowdhury T, Furtwängler R, Graf N, Pritchard-Jones K, Gessler M, Behjati S. Treger TD, et al. Among authors: hutchinson jc. Cancer Discov. 2024 Dec 12. doi: 10.1158/2159-8290.CD-24-0878. Online ahead of print. Cancer Discov. 2024. PMID: 39665570
Macrophage Therapy for Acute Liver Injury (MAIL): a study protocol for a phase 1 randomised, open-label, dose-escalation study to evaluate safety, tolerability and activity of allogeneic alternatively activated macrophages in patients with paracetamol-induced acute liver injury in the UK.
Humphries C, Addison M, Aithal G, Boyd J, Briody L, Campbell JDM, Candela ME, Clarke E, Coulson J, Downing-James N, Fontana RJ, Geddes A, Grahamslaw J, Grant A, Heye A, Hutchinson JA, Jones A, Mitchell F, Moore J, Riddell A, Rodriguez A, Thomas A, Tucker G, Walker K, Weir CJ, Woods R, Zahra S, Forbes SJ, Dear JW. Humphries C, et al. Among authors: hutchinson ja. BMJ Open. 2024 Dec 9;14(12):e089417. doi: 10.1136/bmjopen-2024-089417. BMJ Open. 2024. PMID: 39653576 Free PMC article.
1,620 results