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Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid.
Kansanen E, Jyrkkänen HK, Volger OL, Leinonen H, Kivelä AM, Häkkinen SK, Woodcock SR, Schopfer FJ, Horrevoets AJ, Ylä-Herttuala S, Freeman BA, Levonen AL. Kansanen E, et al. J Biol Chem. 2009 Nov 27;284(48):33233-41. doi: 10.1074/jbc.M109.064873. Epub 2009 Oct 5. J Biol Chem. 2009. PMID: 19808663 Free PMC article.
Clinical applications of vascular gene therapy.
Rutanen J, Rissanen TT, Kivelä A, Vajanto I, Ylä-Herttuala S. Rutanen J, et al. Curr Cardiol Rep. 2001 Jan;3(1):29-36. doi: 10.1007/s11886-001-0007-z. Curr Cardiol Rep. 2001. PMID: 11139796 Review.
Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.
Lehtimäki KK, Valonen PK, Griffin JL, Väisänen TH, Gröhn OH, Kettunen MI, Vepsäläinen J, Ylä-Herttuala S, Nicholson J, Kauppinen RA. Lehtimäki KK, et al. J Biol Chem. 2003 Nov 14;278(46):45915-23. doi: 10.1074/jbc.M306209200. Epub 2003 Sep 3. J Biol Chem. 2003. PMID: 12954643 Free article.
Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo.
Levonen AL, Inkala M, Heikura T, Jauhiainen S, Jyrkkänen HK, Kansanen E, Määttä K, Romppanen E, Turunen P, Rutanen J, Ylä-Herttuala S. Levonen AL, et al. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):741-7. doi: 10.1161/01.ATV.0000258868.80079.4d. Epub 2007 Jan 25. Arterioscler Thromb Vasc Biol. 2007. PMID: 17255530
773 results