Darnay BG - Search Results

1

Structural basis for the lack of E2 interaction in the RING domain of TRAF2.

Yin Q, Lamothe B, Darnay BG, Wu H. Yin Q, et al. Among authors: darnay bg. Biochemistry. 2009 Nov 10;48(44):10558-67. doi: 10.1021/bi901462e. Biochemistry. 2009. PMID: 19810754 Free PMC article.

2

Distinct molecular mechanism for initiating TRAF6 signalling.

Ye H, Arron JR, Lamothe B, Cirilli M, Kobayashi T, Shevde NK, Segal D, Dzivenu OK, Vologodskaia M, Yim M, Du K, Singh S, Pike JW, Darnay BG, Choi Y, Wu H. Ye H, et al. Among authors: darnay bg. Nature. 2002 Jul 25;418(6896):443-7. doi: 10.1038/nature00888. Nature. 2002. PMID: 12140561

3

Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20.

Lin SC, Chung JY, Lamothe B, Rajashankar K, Lu M, Lo YC, Lam AY, Darnay BG, Wu H. Lin SC, et al. Among authors: darnay bg. J Mol Biol. 2008 Feb 15;376(2):526-40. doi: 10.1016/j.jmb.2007.11.092. Epub 2007 Dec 4. J Mol Biol. 2008. PMID: 18164316 Free PMC article.

4

E2 interaction and dimerization in the crystal structure of TRAF6.

Yin Q, Lin SC, Lamothe B, Lu M, Lo YC, Hura G, Zheng L, Rich RL, Campos AD, Myszka DG, Lenardo MJ, Darnay BG, Wu H. Yin Q, et al. Among authors: darnay bg. Nat Struct Mol Biol. 2009 Jun;16(6):658-66. doi: 10.1038/nsmb.1605. Epub 2009 May 24. Nat Struct Mol Biol. 2009. PMID: 19465916 Free PMC article.

5

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.

Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG. Lamothe B, et al. Among authors: darnay bg. J Biol Chem. 2007 Feb 9;282(6):4102-12. doi: 10.1074/jbc.M609503200. Epub 2006 Nov 29. J Biol Chem. 2007. PMID: 17135271 Free PMC article.

6

The RING domain and first zinc finger of TRAF6 coordinate signaling by interleukin-1, lipopolysaccharide, and RANKL.

Lamothe B, Campos AD, Webster WK, Gopinathan A, Hur L, Darnay BG. Lamothe B, et al. Among authors: darnay bg. J Biol Chem. 2008 Sep 5;283(36):24871-80. doi: 10.1074/jbc.M802749200. Epub 2008 Jul 10. J Biol Chem. 2008. PMID: 18617513 Free PMC article.

7

TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation.

Lamothe B, Webster WK, Gopinathan A, Besse A, Campos AD, Darnay BG. Lamothe B, et al. Among authors: darnay bg. Biochem Biophys Res Commun. 2007 Aug 10;359(4):1044-9. doi: 10.1016/j.bbrc.2007.06.017. Epub 2007 Jun 11. Biochem Biophys Res Commun. 2007. PMID: 17572386 Free PMC article.

8

TRAFs in RANK signaling.

Darnay BG, Besse A, Poblenz AT, Lamothe B, Jacoby JJ. Darnay BG, et al. Adv Exp Med Biol. 2007;597:152-9. doi: 10.1007/978-0-387-70630-6_12. Adv Exp Med Biol. 2007. PMID: 17633024 Review.

9

The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK. Yang WL, et al. Among authors: darnay bg. Science. 2009 Aug 28;325(5944):1134-8. doi: 10.1126/science.1175065. Science. 2009. PMID: 19713527 Free PMC article.

10

TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.

Lamothe B, Lai Y, Xie M, Schneider MD, Darnay BG. Lamothe B, et al. Among authors: darnay bg. Mol Cell Biol. 2013 Feb;33(3):582-95. doi: 10.1128/MCB.01225-12. Epub 2012 Nov 19. Mol Cell Biol. 2013. PMID: 23166301 Free PMC article.

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