Mattila E - Search Results

1

Mammary-derived growth inhibitor alters traffic of EGFR and induces a novel form of cetuximab resistance.

Nevo J, Mattila E, Pellinen T, Yamamoto DL, Sara H, Iljin K, Kallioniemi O, Bono P, Heikkilä P, Joensuu H, Wärri A, Ivaska J. Nevo J, et al. Among authors: mattila e. Clin Cancer Res. 2009 Nov 1;15(21):6570-81. doi: 10.1158/1078-0432.CCR-09-0773. Epub 2009 Oct 13. Clin Cancer Res. 2009. PMID: 19825952

2

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.

Mattila E, Pellinen T, Nevo J, Vuoriluoto K, Arjonen A, Ivaska J. Mattila E, et al. Nat Cell Biol. 2005 Jan;7(1):78-85. doi: 10.1038/ncb1209. Epub 2004 Dec 12. Nat Cell Biol. 2005. PMID: 15592458

3

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling.

Mattila E, Auvinen K, Salmi M, Ivaska J. Mattila E, et al. J Cell Sci. 2008 Nov 1;121(Pt 21):3570-80. doi: 10.1242/jcs.031898. Epub 2008 Oct 7. J Cell Sci. 2008. PMID: 18840653

4

CIP2A is associated with human breast cancer aggressivity.

Côme C, Laine A, Chanrion M, Edgren H, Mattila E, Liu X, Jonkers J, Ivaska J, Isola J, Darbon JM, Kallioniemi O, Thézenas S, Westermarck J. Côme C, et al. Among authors: mattila e. Clin Cancer Res. 2009 Aug 15;15(16):5092-100. doi: 10.1158/1078-0432.CCR-08-3283. Epub 2009 Aug 11. Clin Cancer Res. 2009. PMID: 19671842

5

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.

Mattila E, Marttila H, Sahlberg N, Kohonen P, Tähtinen S, Halonen P, Perälä M, Ivaska J. Mattila E, et al. BMC Cancer. 2010 Jan 7;10:7. doi: 10.1186/1471-2407-10-7. BMC Cancer. 2010. PMID: 20055993 Free PMC article.

6

High-throughput methods in identification of protein tyrosine phosphatase inhibitors and activators.

Mattila E, Ivaska J. Mattila E, et al. Anticancer Agents Med Chem. 2011 Jan;11(1):141-50. doi: 10.2174/187152011794941235. Anticancer Agents Med Chem. 2011. PMID: 21288196 Review.

7

SHARPIN is an endogenous inhibitor of β1-integrin activation.

Rantala JK, Pouwels J, Pellinen T, Veltel S, Laasola P, Mattila E, Potter CS, Duffy T, Sundberg JP, Kallioniemi O, Askari JA, Humphries MJ, Parsons M, Salmi M, Ivaska J. Rantala JK, et al. Among authors: mattila e. Nat Cell Biol. 2011 Sep 25;13(11):1315-24. doi: 10.1038/ncb2340. Nat Cell Biol. 2011. PMID: 21947080 Free PMC article.

8

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo.

Högnäs G, Tuomi S, Veltel S, Mattila E, Murumägi A, Edgren H, Kallioniemi O, Ivaska J. Högnäs G, et al. Among authors: mattila e. Oncogene. 2012 Aug 2;31(31):3597-606. doi: 10.1038/onc.2011.527. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120710 Free PMC article.

9

Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.

Ylilauri M, Mattila E, Nurminen EM, Käpylä J, Niinivehmas SP, Määttä JA, Pentikäinen U, Ivaska J, Pentikäinen OT. Ylilauri M, et al. Among authors: mattila e. Biochim Biophys Acta. 2013 Oct;1834(10):1988-97. doi: 10.1016/j.bbapap.2013.07.001. Epub 2013 Jul 12. Biochim Biophys Acta. 2013. PMID: 23856547

10

SHARPIN regulates uropod detachment in migrating lymphocytes.

Pouwels J, De Franceschi N, Rantakari P, Auvinen K, Karikoski M, Mattila E, Potter C, Sundberg JP, Hogg N, Gahmberg CG, Salmi M, Ivaska J. Pouwels J, et al. Among authors: mattila e. Cell Rep. 2013 Nov 14;5(3):619-28. doi: 10.1016/j.celrep.2013.10.011. Epub 2013 Nov 7. Cell Rep. 2013. PMID: 24210817 Free PMC article.

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