Fairlamb AH - Search Results

1

Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis.

Torrie LS, Wyllie S, Spinks D, Oza SL, Thompson S, Harrison JR, Gilbert IH, Wyatt PG, Fairlamb AH, Frearson JA. Torrie LS, et al. Among authors: fairlamb ah. J Biol Chem. 2009 Dec 25;284(52):36137-36145. doi: 10.1074/jbc.M109.045336. Epub 2009 Oct 14. J Biol Chem. 2009. PMID: 19828449 Free PMC article.

2

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei.

Carter NS, Berger BJ, Fairlamb AH. Carter NS, et al. Among authors: fairlamb ah. J Biol Chem. 1995 Nov 24;270(47):28153-7. doi: 10.1074/jbc.270.47.28153. J Biol Chem. 1995. PMID: 7499305 Free article.

3

Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.

Tetaud E, Manai F, Barrett MP, Nadeau K, Walsh CT, Fairlamb AH. Tetaud E, et al. Among authors: fairlamb ah. J Biol Chem. 1998 Jul 31;273(31):19383-90. doi: 10.1074/jbc.273.31.19383. J Biol Chem. 1998. PMID: 9677355 Free article.

4

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes.

Tye CK, Kasinathan G, Barrett MP, Brun R, Doyle VE, Fairlamb AH, Weaver R, Gilbert IH. Tye CK, et al. Among authors: fairlamb ah. Bioorg Med Chem Lett. 1998 Apr 7;8(7):811-6. doi: 10.1016/s0960-894x(98)00095-x. Bioorg Med Chem Lett. 1998. PMID: 9871546

5

The high resolution crystal structure of recombinant Crithidia fasciculata tryparedoxin-I.

Alphey MS, Leonard GA, Gourley DG, Tetaud E, Fairlamb AH, Hunter WN. Alphey MS, et al. Among authors: fairlamb ah. J Biol Chem. 1999 Sep 3;274(36):25613-22. doi: 10.1074/jbc.274.36.25613. J Biol Chem. 1999. PMID: 10464297 Free article.

6

Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata.

Oza SL, Ariyanayagam MR, Fairlamb AH. Oza SL, et al. Among authors: fairlamb ah. Biochem J. 2002 Jun 15;364(Pt 3):679-86. doi: 10.1042/BJ20011370. Biochem J. 2002. PMID: 12049631 Free PMC article.

7

A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.

Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH. Oza SL, et al. Among authors: fairlamb ah. J Biol Chem. 2002 Sep 27;277(39):35853-61. doi: 10.1074/jbc.M204403200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121990 Free article.

8

Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 1: Substitution of the glycine carboxylic acid group.

Amssoms K, Oza SL, Ravaschino E, Yamani A, Lambeir A, Rajan P, Bal G, Rodriguez J, Fairlamb AH, Augustyns K, Haemers A. Amssoms K, et al. Among authors: fairlamb ah. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2553-6. doi: 10.1016/s0960-894x(02)00489-4. Bioorg Med Chem Lett. 2002. PMID: 12182858

9

Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 2: substitution of the glycine part.

Amssoms K, Oza SL, Augustyns K, Yamani A, Lambeir AM, Bal G, Van der Veken P, Fairlamb AH, Haemers A. Amssoms K, et al. Among authors: fairlamb ah. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2703-5. doi: 10.1016/s0960-894x(02)00538-3. Bioorg Med Chem Lett. 2002. PMID: 12217358

10

Properties of phosphoenolpyruvate mutase, the first enzyme in the aminoethylphosphonate biosynthetic pathway in Trypanosoma cruzi.

Sarkar M, Hamilton CJ, Fairlamb AH. Sarkar M, et al. Among authors: fairlamb ah. J Biol Chem. 2003 Jun 20;278(25):22703-8. doi: 10.1074/jbc.M302419200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12672809 Free article.

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