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Page 1
Prevalence of loss-of-function FTO mutations in lean and obese individuals.
Meyre D, Proulx K, Kawagoe-Takaki H, Vatin V, Gutiérrez-Aguilar R, Lyon D, Ma M, Choquet H, Horber F, Van Hul W, Van Gaal L, Balkau B, Visvikis-Siest S, Pattou F, Farooqi IS, Saudek V, O'Rahilly S, Froguel P, Sedgwick B, Yeo GS. Meyre D, et al. Among authors: sedgwick b. Diabetes. 2010 Jan;59(1):311-8. doi: 10.2337/db09-0703. Epub 2009 Oct 15. Diabetes. 2010. PMID: 19833892 Free PMC article.
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations.
Boissel S, Reish O, Proulx K, Kawagoe-Takaki H, Sedgwick B, Yeo GS, Meyre D, Golzio C, Molinari F, Kadhom N, Etchevers HC, Saudek V, Farooqi IS, Froguel P, Lindahl T, O'Rahilly S, Munnich A, Colleaux L. Boissel S, et al. Among authors: sedgwick b. Am J Hum Genet. 2009 Jul;85(1):106-11. doi: 10.1016/j.ajhg.2009.06.002. Epub 2009 Jun 25. Am J Hum Genet. 2009. PMID: 19559399 Free PMC article.
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ. Gerken T, et al. Among authors: sedgwick b. Science. 2007 Nov 30;318(5855):1469-72. doi: 10.1126/science.1151710. Epub 2007 Nov 8. Science. 2007. PMID: 17991826 Free PMC article.
Dynamic states of the DNA repair enzyme AlkB regulate product release.
Bleijlevens B, Shivarattan T, Flashman E, Yang Y, Simpson PJ, Koivisto P, Sedgwick B, Schofield CJ, Matthews SJ. Bleijlevens B, et al. Among authors: sedgwick b. EMBO Rep. 2008 Sep;9(9):872-7. doi: 10.1038/embor.2008.120. Epub 2008 Jul 11. EMBO Rep. 2008. PMID: 18617893 Free PMC article.
Reversal of DNA alkylation damage by two human dioxygenases.
Duncan T, Trewick SC, Koivisto P, Bates PA, Lindahl T, Sedgwick B. Duncan T, et al. Among authors: sedgwick b. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16660-5. doi: 10.1073/pnas.262589799. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486230 Free PMC article.
58 results