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Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis.
Calver JF, Parmar NR, Harris G, Lithgo RM, Stylianou P, Zetterberg FR, Gooptu B, Mackinnon AC, Carr SB, Borthwick LA, Scott DJ, Stewart ID, Slack RJ, Jenkins RG, John AE. Calver JF, et al. Among authors: john ae. J Biol Chem. 2024 Jun;300(6):107300. doi: 10.1016/j.jbc.2024.107300. Epub 2024 Apr 18. J Biol Chem. 2024. PMID: 38641066 Free PMC article.
Multi-Omics Analysis of Glioblastoma and Glioblastoma Cell Line: Molecular Insights Into the Functional Role of GPR56 and TG2 in Mesenchymal Transition.
Ganesh RA, Sonpatki P, Naik D, John AE, Sathe G, Lakshmikantha A, Chandrachari KP, Bauer L, Knäuper V, Aeschlimann D, Venkatraaman K, Shah N, Sirdeshmukh R. Ganesh RA, et al. Among authors: john ae. Front Oncol. 2022 May 3;12:841890. doi: 10.3389/fonc.2022.841890. eCollection 2022. Front Oncol. 2022. PMID: 35600402 Free PMC article.
Lysyl oxidase like 2 is increased in asthma and contributes to asthmatic airway remodelling.
Ramis J, Middlewick R, Pappalardo F, Cairns JT, Stewart ID, John AE, Naveed SU, Krishnan R, Miller S, Shaw DE, Brightling CE, Buttery L, Rose F, Jenkins G, Johnson SR, Tatler AL. Ramis J, et al. Among authors: john ae. Eur Respir J. 2022 Jul 7;60(1):2004361. doi: 10.1183/13993003.04361-2020. Print 2022 Jul. Eur Respir J. 2022. PMID: 34996828 Free PMC article.
Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease.
Wilkinson AL, John AE, Barrett JW, Gower E, Morrison VS, Man Y, Pun KT, Roper JA, Luckett JC, Borthwick LA, Barksby BS, Burgoyne RA, Barnes R, Fisher AJ, Procopiou PA, Hatley RJD, Barrett TN, Marshall RP, Macdonald SJF, Jenkins RG, Slack RJ. Wilkinson AL, et al. Among authors: john ae. Eur J Pharmacol. 2021 Dec 15;913:174618. doi: 10.1016/j.ejphar.2021.174618. Epub 2021 Nov 8. Eur J Pharmacol. 2021. PMID: 34762934
49 results