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Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.
Igata M, Motoshima H, Tsuruzoe K, Kojima K, Matsumura T, Kondo T, Taguchi T, Nakamaru K, Yano M, Kukidome D, Matsumoto K, Toyonaga T, Asano T, Nishikawa T, Araki E. Igata M, et al. Among authors: asano t. Circ Res. 2005 Oct 14;97(8):837-44. doi: 10.1161/01.RES.0000185823.73556.06. Epub 2005 Sep 8. Circ Res. 2005. PMID: 16151020
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.
Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T. Horike N, et al. Among authors: asano t. J Biol Chem. 2008 Dec 5;283(49):33902-10. doi: 10.1074/jbc.M802537200. Epub 2008 Sep 17. J Biol Chem. 2008. PMID: 18801732 Free PMC article.
Growth hormone inhibition of glucose uptake in adipocytes occurs without affecting GLUT4 translocation through an insulin receptor substrate-2-phosphatidylinositol 3-kinase-dependent pathway.
Sasaki-Suzuki N, Arai K, Ogata T, Kasahara K, Sakoda H, Chida K, Asano T, Pessin JE, Hakuno F, Takahashi S. Sasaki-Suzuki N, et al. Among authors: asano t. J Biol Chem. 2009 Mar 6;284(10):6061-70. doi: 10.1074/jbc.M808282200. Epub 2009 Jan 2. J Biol Chem. 2009. PMID: 19122000 Free PMC article.
Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.
Fukushima T, Nakamura Y, Yamanaka D, Shibano T, Chida K, Minami S, Asano T, Hakuno F, Takahashi S. Fukushima T, et al. Among authors: asano t. J Biol Chem. 2012 Aug 24;287(35):29713-21. doi: 10.1074/jbc.M112.393074. Epub 2012 Jul 5. J Biol Chem. 2012. PMID: 22767591 Free PMC article.
Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.
Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: asano t. J Biol Chem. 2015 Oct 2;290(40):24255-66. doi: 10.1074/jbc.M115.658559. Epub 2015 Aug 14. J Biol Chem. 2015. PMID: 26276391 Free PMC article.
Paraquat-induced oxidative stress represses phosphatidylinositol 3-kinase activities leading to impaired glucose uptake in 3T3-L1 adipocytes.
Shibata M, Hakuno F, Yamanaka D, Okajima H, Fukushima T, Hasegawa T, Ogata T, Toyoshima Y, Chida K, Kimura K, Sakoda H, Takenaka A, Asano T, Takahashi S. Shibata M, et al. Among authors: asano t. J Biol Chem. 2010 Jul 2;285(27):20915-25. doi: 10.1074/jbc.M110.126482. Epub 2010 Apr 29. J Biol Chem. 2010. PMID: 20430890 Free PMC article.
2,976 results