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Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway.
Senokuchi T, Matsumura T, Sakai M, Yano M, Taguchi T, Matsuo T, Sonoda K, Kukidome D, Imoto K, Nishikawa T, Kim-Mitsuyama S, Takuwa Y, Araki E. Senokuchi T, et al. Among authors: yano m. J Biol Chem. 2005 Feb 25;280(8):6627-33. doi: 10.1074/jbc.M412531200. Epub 2004 Dec 17. J Biol Chem. 2005. PMID: 15611087 Free article.
Adenosine monophosphate-activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression.
Igata M, Motoshima H, Tsuruzoe K, Kojima K, Matsumura T, Kondo T, Taguchi T, Nakamaru K, Yano M, Kukidome D, Matsumoto K, Toyonaga T, Asano T, Nishikawa T, Araki E. Igata M, et al. Among authors: yano m. Circ Res. 2005 Oct 14;97(8):837-44. doi: 10.1161/01.RES.0000185823.73556.06. Epub 2005 Sep 8. Circ Res. 2005. PMID: 16151020
Statins activate peroxisome proliferator-activated receptor gamma through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages.
Yano M, Matsumura T, Senokuchi T, Ishii N, Murata Y, Taketa K, Motoshima H, Taguchi T, Sonoda K, Kukidome D, Takuwa Y, Kawada T, Brownlee M, Nishikawa T, Araki E. Yano M, et al. Circ Res. 2007 May 25;100(10):1442-51. doi: 10.1161/01.RES.0000268411.49545.9c. Epub 2007 Apr 26. Circ Res. 2007. PMID: 17463321
Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.
Taketa K, Matsumura T, Yano M, Ishii N, Senokuchi T, Motoshima H, Murata Y, Kim-Mitsuyama S, Kawada T, Itabe H, Takeya M, Nishikawa T, Tsuruzoe K, Araki E. Taketa K, et al. Among authors: yano m. J Biol Chem. 2008 Apr 11;283(15):9852-62. doi: 10.1074/jbc.M703318200. Epub 2008 Jan 21. J Biol Chem. 2008. PMID: 18208815 Free article.
2,773 results