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The exon 3-deleted growth hormone receptor is associated with better response to pegvisomant therapy in acromegaly.
Bernabeu I, Alvarez-Escolá C, Quinteiro C, Lucas T, Puig-Domingo M, Luque-Ramírez M, de Miguel-Novoa P, Fernandez-Rodriguez E, Halperin I, Loidi L, Casanueva FF, Marazuela M. Bernabeu I, et al. Among authors: halperin i. J Clin Endocrinol Metab. 2010 Jan;95(1):222-9. doi: 10.1210/jc.2009-1630. Epub 2009 Oct 22. J Clin Endocrinol Metab. 2010. PMID: 19850678
Long-term treatment with pegvisomant for acromegaly: a 10-year experience.
Ramos-Leví AM, Bernabeu I, Álvarez-Escolá C, Aller J, Lucas T, de Miguel P, Rodríguez-Cañete L, Sampedro-Núñez MA, Halperin I, Puig-Domingo M, Marazuela M. Ramos-Leví AM, et al. Among authors: halperin i. Clin Endocrinol (Oxf). 2016 Apr;84(4):540-50. doi: 10.1111/cen.12993. Epub 2016 Jan 26. Clin Endocrinol (Oxf). 2016. PMID: 26662620
Long-term treatment of acromegalic patients resistant to somatostatin analogues with the GH receptor antagonist pegvisomant: its efficacy in relation to gender and previous radiotherapy.
Marazuela M, Lucas T, Alvarez-Escolá C, Puig-Domingo M, de la Torre NG, de Miguel-Novoa P, Duran-Hervada A, Manzanares R, Luque-Ramírez M, Halperin I, Casanueva FF, Bernabeu I. Marazuela M, et al. Among authors: halperin i. Eur J Endocrinol. 2009 Apr;160(4):535-42. doi: 10.1530/EJE-08-0705. Epub 2009 Jan 15. Eur J Endocrinol. 2009. PMID: 19147599
Germline mutations of AIP gene in somatotropinomas resistant to somatostatin analogues.
Oriola J, Lucas T, Halperin I, Mora M, Perales MJ, Alvarez-Escolá C, Paz de MN, Díaz Soto G, Salinas I, Julián MT, Olaizola I, Bernabeu I, Marazuela M, Puig-Domingo M. Oriola J, et al. Among authors: halperin i. Eur J Endocrinol. 2012 Dec 10;168(1):9-13. doi: 10.1530/EJE-12-0457. Print 2013 Jan. Eur J Endocrinol. 2012. PMID: 23038625
Molecular determinants of enhanced response to somatostatin receptor ligands after debulking in large GH-producing adenomas.
Gil J, Marques-Pamies M, Jordà M, Fajardo-Montañana C, García-Martínez A, Sampedro M, Serra G, Salinas I, Blanco A, Valassi E, Sesmilo G, Carrato C, Cámara R, Lamas C, Casano-Sancho P, Alvarez CV, Bernabéu I, Webb SM, Picó A, Marazuela M, Puig-Domingo M; on behalf REMAH investigators. Gil J, et al. Clin Endocrinol (Oxf). 2021 May;94(5):811-819. doi: 10.1111/cen.14339. Epub 2021 Mar 14. Clin Endocrinol (Oxf). 2021. PMID: 32978826
Acromegaly Quality of Life Questionnaire (ACROQOL) a new health-related quality of life questionnaire for patients with acromegaly: development and psychometric properties.
Webb SM, Prieto L, Badia X, Albareda M, Catalá M, Gaztambide S, Lucas T, Páramo C, Picó A, Lucas A, Halperin I, Obiols G, Astorga R. Webb SM, et al. Among authors: halperin i. Clin Endocrinol (Oxf). 2002 Aug;57(2):251-8. doi: 10.1046/j.1365-2265.2002.01597.x. Clin Endocrinol (Oxf). 2002. PMID: 12153605
The efficacy of octreotide LAR as firstline therapy for patients with newly diagnosed acromegaly is independent of tumor extension: predictive factors of tumor and biochemical response.
Luque-Ramírez M, Portoles GR, Varela C, Albero R, Halperin I, Moreiro J, Soto A, Casamitjana R; Spanish Multicentre Group for the Study of Acromegaly. Luque-Ramírez M, et al. Among authors: halperin i. Horm Metab Res. 2010 Jan;42(1):38-44. doi: 10.1055/s-0029-1239506. Epub 2009 Oct 1. Horm Metab Res. 2010. PMID: 19798622 Clinical Trial.
Changes in acromegaly treatment over four decades in Spain: analysis of the Spanish Acromegaly Registry (REA).
Sesmilo G, Gaztambide S, Venegas E, Picó A, Del Pozo C, Blanco C, Torres E, Álvarez-Escolà C, Fajardo C, García R, Cámara R, Bernabeu I, Soto A, Villabona C, Serraclara A, Halperin I, Alcázar V, Palomera E, Webb SM; REA investigators. Sesmilo G, et al. Among authors: halperin i. Pituitary. 2013 Mar;16(1):115-21. doi: 10.1007/s11102-012-0384-x. Pituitary. 2013. PMID: 22481632
276 results