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Both total and phosphorylated tau are increased in Alzheimer's disease.
Sjögren M, Davidsson P, Tullberg M, Minthon L, Wallin A, Wikkelso C, Granérus AK, Vanderstichele H, Vanmechelen E, Blennow K. Sjögren M, et al. Among authors: blennow k. J Neurol Neurosurg Psychiatry. 2001 May;70(5):624-30. doi: 10.1136/jnnp.70.5.624. J Neurol Neurosurg Psychiatry. 2001. PMID: 11309456 Free PMC article.
Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.
Buerger K, Zinkowski R, Teipel SJ, Tapiola T, Arai H, Blennow K, Andreasen N, Hofmann-Kiefer K, DeBernardis J, Kerkman D, McCulloch C, Kohnken R, Padberg F, Pirttilä T, Schapiro MB, Rapoport SI, Möller HJ, Davies P, Hampel H. Buerger K, et al. Among authors: blennow k. Arch Neurol. 2002 Aug;59(8):1267-72. doi: 10.1001/archneur.59.8.1267. Arch Neurol. 2002. PMID: 12164722 Clinical Trial.
Increased frequency of a new polymorphism in the cell division cycle 2 (cdc2) gene in patients with Alzheimer's disease and frontotemporal dementia.
Johansson A, Hampel H, Faltraco F, Buerger K, Minthon L, Bogdanovic N, Sjögren M, Zetterberg H, Forsell L, Lilius L, Wahlund LO, Rymo L, Prince JA, Blennow K. Johansson A, et al. Among authors: blennow k. Neurosci Lett. 2003 Apr 3;340(1):69-73. doi: 10.1016/s0304-3940(03)00051-x. Neurosci Lett. 2003. PMID: 12648761
2,199 results