Ellermann M - Search Results

1

Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor.

Ellermann M, Jakob-Roetne R, Lerner C, Borroni E, Schlatter D, Roth D, Ehler A, Rudolph MG, Diederich F. Ellermann M, et al. Angew Chem Int Ed Engl. 2009;48(48):9092-6. doi: 10.1002/anie.200904410. Angew Chem Int Ed Engl. 2009. PMID: 19882607 No abstract available.

2

Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors.

Ellermann M, Paulini R, Jakob-Roetne R, Lerner C, Borroni E, Roth D, Ehler A, Schweizer WB, Schlatter D, Rudolph MG, Diederich F. Ellermann M, et al. Chemistry. 2011 May 27;17(23):6369-81. doi: 10.1002/chem.201003648. Epub 2011 Apr 27. Chemistry. 2011. PMID: 21538606

3

Aromatic rings in chemical and biological recognition: energetics and structures.

Salonen LM, Ellermann M, Diederich F. Salonen LM, et al. Among authors: ellermann m. Angew Chem Int Ed Engl. 2011 May 16;50(21):4808-42. doi: 10.1002/anie.201007560. Epub 2011 Apr 28. Angew Chem Int Ed Engl. 2011. PMID: 21538733 Review.

4

Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors.

Ellermann M, Lerner C, Burgy G, Ehler A, Bissantz C, Jakob-Roetne R, Paulini R, Allemann O, Tissot H, Grünstein D, Stihle M, Diederich F, Rudolph MG. Ellermann M, et al. Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):253-60. doi: 10.1107/S0907444912001138. Epub 2012 Feb 14. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22349227

5

Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn's disease.

Ahn JH, da Silva Pedrosa M, Lopez LR, Tibbs TN, Jeyachandran JN, Vignieri EE, Rothemich A, Cumming I, Irmscher AD, Haswell CJ, Zamboni WC, Yu YA, Ellermann M, Denson LA, Arthur JC. Ahn JH, et al. Among authors: ellermann m. Cell Host Microbe. 2025 Jan 8;33(1):71-88.e9. doi: 10.1016/j.chom.2024.11.012. Epub 2024 Dec 18. Cell Host Microbe. 2025. PMID: 39701098 Free article.

6

Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10 -deficient mouse model.

Older EA, Mitchell MK, Campbell A, Lian X, Madden M, Wang Y, van de Wal LE, Zaw T, VanderVeen BN, Tatum R, Murphy EA, Chen YH, Fan D, Ellermann M, Li J. Older EA, et al. Among authors: ellermann m. bioRxiv [Preprint]. 2024 Oct 24:2024.10.23.619966. doi: 10.1101/2024.10.23.619966. bioRxiv. 2024. PMID: 39484420 Free PMC article. Preprint.

7

Biosynthetic enzyme analysis identifies a protective role for TLR4-acting gut microbial sulfonolipids in inflammatory bowel disease.

Older EA, Zhang J, Ferris ZE, Xue D, Zhong Z, Mitchell MK, Madden M, Wang Y, Chen H, Nagarkatti P, Nagarkatti M, Fan D, Ellermann M, Li YX, Li J. Older EA, et al. Among authors: ellermann m. Nat Commun. 2024 Oct 30;15(1):9371. doi: 10.1038/s41467-024-53670-y. Nat Commun. 2024. PMID: 39477928 Free PMC article.

8

Discovery of BAY 2666605, a Molecular Glue for PDE3A and SLFN12.

Lewis TA, Ellermann M, Kopitz C, Lange M, de Waal L, Wu X, Tersteegen A, Denner K, Lienau P, Kaulfuss S, Goldoni S, Meyerson M, Greulich H, Gradl SN. Lewis TA, et al. Among authors: ellermann m. ACS Med Chem Lett. 2024 Sep 10;15(10):1662-1667. doi: 10.1021/acsmedchemlett.4c00336. eCollection 2024 Oct 10. ACS Med Chem Lett. 2024. PMID: 39411532

9

Emerging mechanisms by which endocannabinoids and their derivatives modulate bacterial populations within the gut microbiome.

Ellermann M. Ellermann M. Adv Drug Alcohol Res. 2023 Dec 8;3:11359. doi: 10.3389/adar.2023.11359. eCollection 2023. Adv Drug Alcohol Res. 2023. PMID: 38389811 Free PMC article. Review.

10

Designing microbial communities to starve out invading pathogens.

Ellermann M. Ellermann M. Cell Host Microbe. 2024 Feb 14;32(2):145-146. doi: 10.1016/j.chom.2024.01.008. Cell Host Microbe. 2024. PMID: 38359793

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