Toombs JE - Search Results

1

Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer.

Roland CL, Lynn KD, Toombs JE, Dineen SP, Udugamasooriya DG, Brekken RA. Roland CL, et al. Among authors: toombs je. PLoS One. 2009 Nov 3;4(11):e7669. doi: 10.1371/journal.pone.0007669. PLoS One. 2009. PMID: 19888452 Free PMC article.

2

The acellular fraction of stored platelets promotes tumor cell invasion.

Dineen SP, Roland CL, Toombs JE, Kelher M, Silliman CC, Brekken RA, Barnett CC Jr. Dineen SP, et al. Among authors: toombs je. J Surg Res. 2009 May 1;153(1):132-7. doi: 10.1016/j.jss.2008.04.013. Epub 2008 May 7. J Surg Res. 2009. PMID: 18541268

3

Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer.

Dineen SP, Roland CL, Greer R, Carbon JG, Toombs JE, Gupta P, Bardeesy N, Sun H, Williams N, Minna JD, Brekken RA. Dineen SP, et al. Among authors: toombs je. Cancer Res. 2010 Apr 1;70(7):2852-61. doi: 10.1158/0008-5472.CAN-09-3892. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332237 Free PMC article.

4

Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts.

Roland CL, Dineen SP, Toombs JE, Carbon JG, Smith CW, Brekken RA, Barnett CC Jr. Roland CL, et al. Among authors: toombs je. Exp Biol Med (Maywood). 2010 Feb;235(2):263-70. doi: 10.1258/ebm.2009.009215. Exp Biol Med (Maywood). 2010. PMID: 20404043

5

r84, a novel therapeutic antibody against mouse and human VEGF with potent anti-tumor activity and limited toxicity induction.

Sullivan LA, Carbon JG, Roland CL, Toombs JE, Nyquist-Andersen M, Kavlie A, Schlunegger K, Richardson JA, Brekken RA. Sullivan LA, et al. Among authors: toombs je. PLoS One. 2010 Aug 6;5(8):e12031. doi: 10.1371/journal.pone.0012031. PLoS One. 2010. PMID: 20700512 Free PMC article.

6

Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer.

Awasthi N, Kirane A, Schwarz MA, Toombs JE, Brekken RA, Schwarz RE. Awasthi N, et al. Among authors: toombs je. BMC Cancer. 2011 Jan 12;11:15. doi: 10.1186/1471-2407-11-15. BMC Cancer. 2011. PMID: 21226944 Free PMC article.

7

Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation.

Arnold SA, Rivera LB, Carbon JG, Toombs JE, Chang CL, Bradshaw AD, Brekken RA. Arnold SA, et al. Among authors: toombs je. PLoS One. 2012;7(2):e31384. doi: 10.1371/journal.pone.0031384. Epub 2012 Feb 14. PLoS One. 2012. PMID: 22348081 Free PMC article.

8

Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.

Kirane A, Toombs JE, Larsen JE, Ostapoff KT, Meshaw KR, Zaknoen S, Brekken RA, Burrows FJ. Kirane A, et al. Among authors: toombs je. Carcinogenesis. 2012 Sep;33(9):1639-46. doi: 10.1093/carcin/bgs195. Epub 2012 Jun 7. Carcinogenesis. 2012. PMID: 22678114 Free PMC article.

9

Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.

Kirane A, Toombs JE, Ostapoff K, Carbon JG, Zaknoen S, Braunfeld J, Schwarz RE, Burrows FJ, Brekken RA. Kirane A, et al. Among authors: toombs je. Clin Cancer Res. 2012 Sep 15;18(18):5031-42. doi: 10.1158/1078-0432.CCR-12-0453. Epub 2012 Jul 24. Clin Cancer Res. 2012. PMID: 22829202 Free PMC article.

10

Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts.

Gerber DE, Gupta P, Dellinger MT, Toombs JE, Peyton M, Duignan I, Malaby J, Bailey T, Burns C, Brekken RA, Loizos N. Gerber DE, et al. Among authors: toombs je. Mol Cancer Ther. 2012 Nov;11(11):2473-82. doi: 10.1158/1535-7163.MCT-12-0431. Epub 2012 Aug 28. Mol Cancer Ther. 2012. PMID: 22933705 Free PMC article.

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