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Heparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearance.
Stanford KI, Wang L, Castagnola J, Song D, Bishop JR, Brown JR, Lawrence R, Bai X, Habuchi H, Tanaka M, Cardoso WV, Kimata K, Esko JD. Stanford KI, et al. Among authors: wang l. J Biol Chem. 2010 Jan 1;285(1):286-94. doi: 10.1074/jbc.M109.063701. Epub 2009 Nov 4. J Biol Chem. 2010. PMID: 19889634 Free PMC article.
Binding and uptake of the lipoproteins by way of heparan sulfate depends on the degree of sulfation of the chains based on accumulation of plasma triglycerides and delayed clearance of triglyceride-rich lipoproteins in mice bearing a hepatocyte-specific alteration of N-acetylgluc …
Binding and uptake of the lipoproteins by way of heparan sulfate depends on the degree of sulfation of the chains based on accumulation of p …
Surfen, a small molecule antagonist of heparan sulfate.
Schuksz M, Fuster MM, Brown JR, Crawford BE, Ditto DP, Lawrence R, Glass CA, Wang L, Tor Y, Esko JD. Schuksz M, et al. Among authors: wang l. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80. doi: 10.1073/pnas.0805862105. Epub 2008 Aug 25. Proc Natl Acad Sci U S A. 2008. PMID: 18725627 Free PMC article.
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