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Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.
Takahashi N, Goto T, Taimatsu A, Egawa K, Katoh S, Kusudo T, Sakamoto T, Ohyane C, Lee JY, Kim YI, Uemura T, Hirai S, Kawada T. Takahashi N, et al. Among authors: lee jy. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1372-6. doi: 10.1016/j.bbrc.2009.10.162. Epub 2009 Nov 3. Biochem Biophys Res Commun. 2009. PMID: 19891958
Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways.
Goto T, Kim YI, Funakoshi K, Teraminami A, Uemura T, Hirai S, Lee JY, Makishima M, Nakata R, Inoue H, Senju H, Matsunaga M, Horio F, Takahashi N, Kawada T. Goto T, et al. Among authors: lee jy. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E1022-32. doi: 10.1152/ajpendo.00061.2011. Epub 2011 Aug 23. Am J Physiol Endocrinol Metab. 2011. PMID: 21862726 Free article.
Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice.
Goto T, Teraminami A, Lee JY, Ohyama K, Funakoshi K, Kim YI, Hirai S, Uemura T, Yu R, Takahashi N, Kawada T. Goto T, et al. Among authors: lee jy. J Nutr Biochem. 2012 Jul;23(7):768-76. doi: 10.1016/j.jnutbio.2011.04.001. Epub 2011 Sep 1. J Nutr Biochem. 2012. PMID: 21889885
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