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Page 1
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.
Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. Andrews ZB, et al. Nature. 2008 Aug 14;454(7206):846-51. doi: 10.1038/nature07181. Epub 2008 Jul 30. Nature. 2008. PMID: 18668043 Free PMC article.
Uncoupling protein-2 decreases the lipogenic actions of ghrelin.
Andrews ZB, Erion DM, Beiler R, Choi CS, Shulman GI, Horvath TL. Andrews ZB, et al. Endocrinology. 2010 May;151(5):2078-86. doi: 10.1210/en.2009-0850. Epub 2010 Feb 26. Endocrinology. 2010. PMID: 20189996 Free PMC article.
SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats.
Erion DM, Yonemitsu S, Nie Y, Nagai Y, Gillum MP, Hsiao JJ, Iwasaki T, Stark R, Weismann D, Yu XX, Murray SF, Bhanot S, Monia BP, Horvath TL, Gao Q, Samuel VT, Shulman GI. Erion DM, et al. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11288-93. doi: 10.1073/pnas.0812931106. Epub 2009 Jun 22. Proc Natl Acad Sci U S A. 2009. PMID: 19549853 Free PMC article.
STAT3 inhibition of gluconeogenesis is downregulated by SirT1.
Nie Y, Erion DM, Yuan Z, Dietrich M, Shulman GI, Horvath TL, Gao Q. Nie Y, et al. Nat Cell Biol. 2009 Apr;11(4):492-500. doi: 10.1038/ncb1857. Epub 2009 Mar 22. Nat Cell Biol. 2009. PMID: 19295512 Free PMC article.
Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism.
Brown WH, Gillum MP, Lee HY, Camporez JP, Zhang XM, Jeong JK, Alves TC, Erion DM, Guigni BA, Kahn M, Samuel VT, Cravatt BF, Diano S, Shulman GI. Brown WH, et al. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14966-71. doi: 10.1073/pnas.1212887109. Epub 2012 Aug 21. Proc Natl Acad Sci U S A. 2012. PMID: 22912404 Free PMC article.
The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.
Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D, Dong J, Zhang D, Jurczak MJ, Löffler MG, Cresswell J, Yu XX, Murray SF, Bhanot S, Monia BP, Bogan JS, Samuel V, Shulman GI. Nagai Y, et al. Among authors: erion dm. Cell Metab. 2009 Mar;9(3):252-64. doi: 10.1016/j.cmet.2009.01.011. Cell Metab. 2009. PMID: 19254570 Free PMC article.
47 results