Thurmond RL - Search Results

1

The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation.

Cowden JM, Zhang M, Dunford PJ, Thurmond RL. Cowden JM, et al. Among authors: thurmond rl. J Invest Dermatol. 2010 Apr;130(4):1023-33. doi: 10.1038/jid.2009.358. Epub 2009 Nov 12. J Invest Dermatol. 2010. PMID: 19907432 Free article.

2

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.

Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W, Nguyen S, Riley JP, Sun S, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13. doi: 10.1124/jpet.103.061754. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722321

3

Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists.

Venable JD, Cai H, Chai W, Dvorak CA, Grice CA, Jablonowski JA, Shah CR, Kwok AK, Ly KS, Pio B, Wei J, Desai PJ, Jiang W, Nguyen S, Ling P, Wilson SJ, Dunford PJ, Thurmond RL, Lovenberg TW, Karlsson L, Carruthers NI, Edwards JP. Venable JD, et al. Among authors: thurmond rl. J Med Chem. 2005 Dec 29;48(26):8289-98. doi: 10.1021/jm0502081. J Med Chem. 2005. PMID: 16366610

4

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.

Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. Dunford PJ, et al. Among authors: thurmond rl. J Immunol. 2006 Jun 1;176(11):7062-70. doi: 10.4049/jimmunol.176.11.7062. J Immunol. 2006. PMID: 16709868

5

The histamine H4 receptor in autoimmune disease.

Zhang M, Venable JD, Thurmond RL. Zhang M, et al. Among authors: thurmond rl. Expert Opin Investig Drugs. 2006 Nov;15(11):1443-52. doi: 10.1517/13543784.15.11.1443. Expert Opin Investig Drugs. 2006. PMID: 17040202 Review.

6

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus.

Dunford PJ, Williams KN, Desai PJ, Karlsson L, McQueen D, Thurmond RL. Dunford PJ, et al. Among authors: thurmond rl. J Allergy Clin Immunol. 2007 Jan;119(1):176-83. doi: 10.1016/j.jaci.2006.08.034. Epub 2006 Oct 13. J Allergy Clin Immunol. 2007. PMID: 17208599

7

The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders.

Zhang M, Thurmond RL, Dunford PJ. Zhang M, et al. Among authors: thurmond rl. Pharmacol Ther. 2007 Mar;113(3):594-606. doi: 10.1016/j.pharmthera.2006.11.008. Epub 2006 Dec 28. Pharmacol Ther. 2007. PMID: 17275092 Review.

8

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines.

Thurmond RL, Gelfand EW, Dunford PJ. Thurmond RL, et al. Nat Rev Drug Discov. 2008 Jan;7(1):41-53. doi: 10.1038/nrd2465. Nat Rev Drug Discov. 2008. PMID: 18172439 Review.

9

Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines.

Cowden JM, Riley JP, Ma JY, Thurmond RL, Dunford PJ. Cowden JM, et al. Among authors: thurmond rl. Respir Res. 2010 Jun 24;11(1):86. doi: 10.1186/1465-9921-11-86. Respir Res. 2010. PMID: 20573261 Free PMC article.

10

Tricyclic aminopyrimidine histamine H4 receptor antagonists.

Savall BM, Gomez L, Chavez F, Curtis M, Meduna SP, Kearney A, Dunford P, Cowden J, Thurmond RL, Grice C, Edwards JP. Savall BM, et al. Among authors: thurmond rl. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6577-81. doi: 10.1016/j.bmcl.2011.08.014. Epub 2011 Aug 19. Bioorg Med Chem Lett. 2011. PMID: 21920744

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