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Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
Fickert P, Fuchsbichler A, Moustafa T, Wagner M, Zollner G, Halilbasic E, Stöger U, Arrese M, Pizarro M, Solís N, Carrasco G, Caligiuri A, Sombetzki M, Reisinger E, Tsybrovskyy O, Zatloukal K, Denk H, Jaeschke H, Pinzani M, Trauner M. Fickert P, et al. Among authors: moustafa t. Am J Pathol. 2009 Dec;175(6):2392-405. doi: 10.2353/ajpath.2009.090114. Epub 2009 Nov 12. Am J Pathol. 2009. PMID: 19910507 Free PMC article.
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Zollner G, Wagner M, Moustafa T, Fickert P, Silbert D, Gumhold J, Fuchsbichler A, Halilbasic E, Denk H, Marschall HU, Trauner M. Zollner G, et al. Among authors: moustafa t. Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G923-32. doi: 10.1152/ajpgi.00490.2005. Epub 2005 Dec 15. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16357057 Free article.
Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
Boyer JL, Trauner M, Mennone A, Soroka CJ, Cai SY, Moustafa T, Zollner G, Lee JY, Ballatori N. Boyer JL, et al. Among authors: moustafa t. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1124-30. doi: 10.1152/ajpgi.00539.2005. Epub 2006 Jan 19. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16423920 Free article.
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Fickert P, Stöger U, Fuchsbichler A, Moustafa T, Marschall HU, Weiglein AH, Tsybrovskyy O, Jaeschke H, Zatloukal K, Denk H, Trauner M. Fickert P, et al. Among authors: moustafa t. Am J Pathol. 2007 Aug;171(2):525-36. doi: 10.2353/ajpath.2007.061133. Epub 2007 Jun 28. Am J Pathol. 2007. PMID: 17600122 Free PMC article.
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Halilbasic E, Fiorotto R, Fickert P, Marschall HU, Moustafa T, Spirli C, Fuchsbichler A, Gumhold J, Silbert D, Zatloukal K, Langner C, Maitra U, Denk H, Hofmann AF, Strazzabosco M, Trauner M. Halilbasic E, et al. Among authors: moustafa t. Hepatology. 2009 Jun;49(6):1972-81. doi: 10.1002/hep.22891. Hepatology. 2009. PMID: 19475687 Free PMC article.
62 results