Li H - Search Results

1

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.

Evrin C, Clarke P, Zech J, Lurz R, Sun J, Uhle S, Li H, Stillman B, Speck C. Evrin C, et al. Among authors: li h. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20240-5. doi: 10.1073/pnas.0911500106. Epub 2009 Nov 12. Proc Natl Acad Sci U S A. 2009. PMID: 19910535 Free PMC article.

2

ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

Speck C, Chen Z, Li H, Stillman B. Speck C, et al. Among authors: li h. Nat Struct Mol Biol. 2005 Nov;12(11):965-71. doi: 10.1038/nsmb1002. Nat Struct Mol Biol. 2005. PMID: 16228006 Free PMC article.

3

The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae.

Chen Z, Speck C, Wendel P, Tang C, Stillman B, Li H. Chen Z, et al. Among authors: li h. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10326-31. doi: 10.1073/pnas.0803829105. Epub 2008 Jul 22. Proc Natl Acad Sci U S A. 2008. PMID: 18647841 Free PMC article.

4

How to operate a cryo-electron microscope.

Sun J, Li H. Sun J, et al. Among authors: li h. Methods Enzymol. 2010;481:231-49. doi: 10.1016/S0076-6879(10)81010-9. Methods Enzymol. 2010. PMID: 20887860

5

Cdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopy.

Sun J, Kawakami H, Zech J, Speck C, Stillman B, Li H. Sun J, et al. Among authors: li h. Structure. 2012 Mar 7;20(3):534-44. doi: 10.1016/j.str.2012.01.011. Structure. 2012. PMID: 22405012 Free PMC article.

6

The origin recognition complex: a biochemical and structural view.

Li H, Stillman B. Li H, et al. Subcell Biochem. 2012;62:37-58. doi: 10.1007/978-94-007-4572-8_3. Subcell Biochem. 2012. PMID: 22918579 Free PMC article. Review.

7

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

Sun J, Evrin C, Samel SA, Fernández-Cid A, Riera A, Kawakami H, Stillman B, Speck C, Li H. Sun J, et al. Among authors: li h. Nat Struct Mol Biol. 2013 Aug;20(8):944-51. doi: 10.1038/nsmb.2629. Epub 2013 Jul 14. Nat Struct Mol Biol. 2013. PMID: 23851460 Free PMC article.

8

Seeing is believing: the MCM2-7 helicase trapped in complex with its DNA loader.

Riera A, Li H, Speck C. Riera A, et al. Among authors: li h. Cell Cycle. 2013 Sep 15;12(18):2917-8. doi: 10.4161/cc.26132. Epub 2013 Aug 21. Cell Cycle. 2013. PMID: 23974098 Free PMC article. No abstract available.

9

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.

Samel SA, Fernández-Cid A, Sun J, Riera A, Tognetti S, Herrera MC, Li H, Speck C. Samel SA, et al. Among authors: li h. Genes Dev. 2014 Aug 1;28(15):1653-66. doi: 10.1101/gad.242404.114. Genes Dev. 2014. PMID: 25085418 Free PMC article.

10

Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.

Sun J, Fernandez-Cid A, Riera A, Tognetti S, Yuan Z, Stillman B, Speck C, Li H. Sun J, et al. Among authors: li h. Genes Dev. 2014 Oct 15;28(20):2291-303. doi: 10.1101/gad.242313.114. Genes Dev. 2014. PMID: 25319829 Free PMC article.

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