Fairlamb AH - Search Results

1

Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.

Spinks D, Shanks EJ, Cleghorn LA, McElroy S, Jones D, James D, Fairlamb AH, Frearson JA, Wyatt PG, Gilbert IH. Spinks D, et al. Among authors: fairlamb ah. ChemMedChem. 2009 Dec;4(12):2060-9. doi: 10.1002/cmdc.200900262. ChemMedChem. 2009. PMID: 19924760 Free PMC article.

2

Rational design of selective ligands for trypanothione reductase from Trypanosoma cruzi. Structural effects on the inhibition by dibenzazepines based on imipramine.

Garforth J, Yin H, McKie JH, Douglas KT, Fairlamb AH. Garforth J, et al. Among authors: fairlamb ah. J Enzyme Inhib. 1997 Aug;12(3):161-73. doi: 10.3109/14756369709029312. J Enzyme Inhib. 1997. PMID: 9314113

3

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes.

Tye CK, Kasinathan G, Barrett MP, Brun R, Doyle VE, Fairlamb AH, Weaver R, Gilbert IH. Tye CK, et al. Among authors: fairlamb ah. Bioorg Med Chem Lett. 1998 Apr 7;8(7):811-6. doi: 10.1016/s0960-894x(98)00095-x. Bioorg Med Chem Lett. 1998. PMID: 9871546

4

Ovothiol and trypanothione as antioxidants in trypanosomatids.

Ariyanayagam MR, Fairlamb AH. Ariyanayagam MR, et al. Among authors: fairlamb ah. Mol Biochem Parasitol. 2001 Jul;115(2):189-98. doi: 10.1016/s0166-6851(01)00285-7. Mol Biochem Parasitol. 2001. PMID: 11420105

5

Molecular characterisation of mitochondrial and cytosolic trypanothione-dependent tryparedoxin peroxidases in Trypanosoma brucei.

Tetaud E, Giroud C, Prescott AR, Parkin DW, Baltz D, Biteau N, Baltz T, Fairlamb AH. Tetaud E, et al. Among authors: fairlamb ah. Mol Biochem Parasitol. 2001 Sep 3;116(2):171-83. doi: 10.1016/s0166-6851(01)00320-6. Mol Biochem Parasitol. 2001. PMID: 11522350

6

Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase.

Hamilton CJ, Saravanamuthu A, Eggleston IM, Fairlamb AH. Hamilton CJ, et al. Among authors: fairlamb ah. Biochem J. 2003 Feb 1;369(Pt 3):529-37. doi: 10.1042/BJ20021298. Biochem J. 2003. PMID: 12416994 Free PMC article.

7

Benzofuranyl 3,5-bis-polyamine derivatives as time-dependent inhibitors of trypanothione reductase.

Hamilton CJ, Saravanamuthu A, Fairlamb AH, Eggleston IM. Hamilton CJ, et al. Among authors: fairlamb ah. Bioorg Med Chem. 2003 Aug 15;11(17):3683-93. doi: 10.1016/s0968-0896(03)00344-4. Bioorg Med Chem. 2003. PMID: 12901914

8

Properties of trypanothione synthetase from Trypanosoma brucei.

Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH. Oza SL, et al. Among authors: fairlamb ah. Mol Biochem Parasitol. 2003 Sep;131(1):25-33. doi: 10.1016/s0166-6851(03)00176-2. Mol Biochem Parasitol. 2003. PMID: 12967709

9

Trypanothione S-transferase activity in a trypanosomatid ribosomal elongation factor 1B.

Vickers TJ, Fairlamb AH. Vickers TJ, et al. Among authors: fairlamb ah. J Biol Chem. 2004 Jun 25;279(26):27246-56. doi: 10.1074/jbc.M311039200. Epub 2004 Apr 8. J Biol Chem. 2004. PMID: 15073172 Free PMC article.

10

Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design.

Saravanamuthu A, Vickers TJ, Bond CS, Peterson MR, Hunter WN, Fairlamb AH. Saravanamuthu A, et al. Among authors: fairlamb ah. J Biol Chem. 2004 Jul 9;279(28):29493-500. doi: 10.1074/jbc.M403187200. Epub 2004 Apr 21. J Biol Chem. 2004. PMID: 15102853 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

264 results

Search Page

Filters