Impact of disease-causing SUR1 mutations on the KATP channel subunit interface probed with a rhodamine protection assay.
Hosy E, Dupuis JP, Vivaudou M.
Hosy E, et al. Among authors: vivaudou m.
J Biol Chem. 2010 Jan 29;285(5):3084-91. doi: 10.1074/jbc.M109.043307. Epub 2009 Nov 20.
J Biol Chem. 2010.
PMID: 19933268
Free PMC article.
The conformation of the interface between these two subunits can be monitored using a rhodamine 123 (Rho) protection assay because Rho blocks Kir6.2 with an efficiency that depends on the relative position of transmembrane domain (TMD) 0 of the associated SUR (Hosy, E., Derand, R …
The conformation of the interface between these two subunits can be monitored using a rhodamine 123 (Rho) protection assay because Rho block …