Ní Gabhann J - Search Results

1

Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.

Boyd CR, Orr SJ, Spence S, Burrows JF, Elliott J, Carroll HP, Brennan K, Ní Gabhann J, Coulter WA, Jones C, Crocker PR, Johnston JA, Jefferies CA. Boyd CR, et al. Among authors: ni gabhann j. J Immunol. 2009 Dec 15;183(12):7703-9. doi: 10.4049/jimmunol.0902780. J Immunol. 2009. PMID: 19933851 Free PMC article.

2

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3.

Higgs R, Ní Gabhann J, Ben Larbi N, Breen EP, Fitzgerald KA, Jefferies CA. Higgs R, et al. Among authors: ni gabhann j. J Immunol. 2008 Aug 1;181(3):1780-6. doi: 10.4049/jimmunol.181.3.1780. J Immunol. 2008. PMID: 18641315 Free PMC article.

3

Btk regulates macrophage polarization in response to lipopolysaccharide.

Ní Gabhann J, Hams E, Smith S, Wynne C, Byrne JC, Brennan K, Spence S, Kissenpfennig A, Johnston JA, Fallon PG, Jefferies CA. Ní Gabhann J, et al. PLoS One. 2014 Jan 21;9(1):e85834. doi: 10.1371/journal.pone.0085834. eCollection 2014. PLoS One. 2014. PMID: 24465735 Free PMC article.

4

Bruton's tyrosine kinase is required for apoptotic cell uptake via regulating the phosphorylation and localization of calreticulin.

Byrne JC, Ní Gabhann J, Stacey KB, Coffey BM, McCarthy E, Thomas W, Jefferies CA. Byrne JC, et al. Among authors: ni gabhann j. J Immunol. 2013 May 15;190(10):5207-15. doi: 10.4049/jimmunol.1300057. Epub 2013 Apr 17. J Immunol. 2013. PMID: 23596312

5

TLR-induced activation of Btk -- role for endosomal MHC class II molecules revealed.

Ní Gabhann J, Jefferies CA. Ní Gabhann J, et al. Cell Res. 2011 Jul;21(7):998-1001. doi: 10.1038/cr.2011.88. Epub 2011 May 24. Cell Res. 2011. PMID: 21606951 Free PMC article. No abstract available.

6

Defects in acute responses to TLR4 in Btk-deficient mice result in impaired dendritic cell-induced IFN-γ production by natural killer cells.

Ní Gabhann J, Spence S, Wynne C, Smith S, Byrne JC, Coffey B, Stacey K, Kissenpfennig A, Johnston J, Jefferies CA. Ní Gabhann J, et al. Clin Immunol. 2012 Mar;142(3):373-82. doi: 10.1016/j.clim.2011.12.009. Epub 2011 Dec 28. Clin Immunol. 2012. PMID: 22281426

7

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors.

Higgs R, Lazzari E, Wynne C, Ní Gabhann J, Espinosa A, Wahren-Herlenius M, Jefferies CA. Higgs R, et al. Among authors: ni gabhann j. PLoS One. 2010 Jul 26;5(7):e11776. doi: 10.1371/journal.pone.0011776. PLoS One. 2010. PMID: 20668674 Free PMC article.

8

TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.

Lazzari E, Korczeniewska J, Ní Gabhann J, Smith S, Barnes BJ, Jefferies CA. Lazzari E, et al. Among authors: ni gabhann j. PLoS One. 2014 Aug 1;9(8):e103609. doi: 10.1371/journal.pone.0103609. eCollection 2014. PLoS One. 2014. PMID: 25084355 Free PMC article.

9

Genetics of SLE: functional relevance for monocytes/macrophages in disease.

Byrne JC, Ní Gabhann J, Lazzari E, Mahony R, Smith S, Stacey K, Wynne C, Jefferies CA. Byrne JC, et al. Among authors: ni gabhann j. Clin Dev Immunol. 2012;2012:582352. doi: 10.1155/2012/582352. Epub 2012 Oct 16. Clin Dev Immunol. 2012. PMID: 23227085 Free PMC article. Review.

10

TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems.

Wynne C, Lazzari E, Smith S, McCarthy EM, Ní Gabhann J, Kallal LE, Higgs R, Greco A, Cryan SA, Biron CA, Jefferies CA. Wynne C, et al. Among authors: ni gabhann j. PLoS One. 2014 Jul 7;9(7):e101503. doi: 10.1371/journal.pone.0101503. eCollection 2014. PLoS One. 2014. PMID: 24999993 Free PMC article.

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