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SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Buchanan SG, Hendle J, Lee PS, Smith CR, Bounaud PY, Jessen KA, Tang CM, Huser NH, Felce JD, Froning KJ, Peterman MC, Aubol BE, Gessert SF, Sauder JM, Schwinn KD, Russell M, Rooney IA, Adams J, Leon BC, Do TH, Blaney JM, Sprengeler PA, Thompson DA, Smyth L, Pelletier LA, Atwell S, Holme K, Wasserman SR, Emtage S, Burley SK, Reich SH. Buchanan SG, et al. Among authors: adams j. Mol Cancer Ther. 2009 Dec;8(12):3181-90. doi: 10.1158/1535-7163.MCT-09-0477. Mol Cancer Ther. 2009. PMID: 19934279
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.
Atwell S, Adams JM, Badger J, Buchanan MD, Feil IK, Froning KJ, Gao X, Hendle J, Keegan K, Leon BC, Müller-Dieckmann HJ, Nienaber VL, Noland BW, Post K, Rajashankar KR, Ramos A, Russell M, Burley SK, Buchanan SG. Atwell S, et al. Among authors: adams jm. J Biol Chem. 2004 Dec 31;279(53):55827-32. doi: 10.1074/jbc.M409792200. Epub 2004 Oct 26. J Biol Chem. 2004. PMID: 15507431 Free article.
Structural analysis of a set of proteins resulting from a bacterial genomics project.
Badger J, Sauder JM, Adams JM, Antonysamy S, Bain K, Bergseid MG, Buchanan SG, Buchanan MD, Batiyenko Y, Christopher JA, Emtage S, Eroshkina A, Feil I, Furlong EB, Gajiwala KS, Gao X, He D, Hendle J, Huber A, Hoda K, Kearins P, Kissinger C, Laubert B, Lewis HA, Lin J, Loomis K, Lorimer D, Louie G, Maletic M, Marsh CD, Miller I, Molinari J, Muller-Dieckmann HJ, Newman JM, Noland BW, Pagarigan B, Park F, Peat TS, Post KW, Radojicic S, Ramos A, Romero R, Rutter ME, Sanderson WE, Schwinn KD, Tresser J, Winhoven J, Wright TA, Wu L, Xu J, Harris TJ. Badger J, et al. Among authors: adams jm. Proteins. 2005 Sep 1;60(4):787-96. doi: 10.1002/prot.20541. Proteins. 2005. PMID: 16021622
Effects of MCL-1 expression in colorectal cancer.
Adams J, Stebbing J. Adams J, et al. Int J Cancer. 2024 Dec 30. doi: 10.1002/ijc.35308. Online ahead of print. Int J Cancer. 2024. PMID: 39740067 No abstract available.
The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.
Zhang Z, Lyu M, Han X, Bandara S, Cui M, Istvan ES, Geng X, Tringides ML, Gregor WD, Miyagi M, Oberstaller J, Adams JH, Zhang Y, Nieman MT, von Lintig J, Goldberg DE, Yu EW. Zhang Z, et al. Among authors: adams jh. Sci Adv. 2024 Dec 20;10(51):eadq6651. doi: 10.1126/sciadv.adq6651. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693420 Free PMC article.
Structured tailored rehabilitation after hip fragility fracture: The 'Stratify' feasibility and pilot randomised controlled trial protocol.
Sheehan KJ, Guerra S, Ayis S, Goubar A, Foster NE, Martin FC, Godfrey E, Cameron ID, Gregson CL, Walsh NE, Ferguson Montague A, Edwards R, Adams J, Jones GD, Gibson J, Sackley C, Whitney J. Sheehan KJ, et al. Among authors: adams j. PLoS One. 2024 Dec 17;19(12):e0306870. doi: 10.1371/journal.pone.0306870. eCollection 2024. PLoS One. 2024. PMID: 39689129 Free PMC article. Clinical Trial.
8,017 results