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mTOR and cancer: many loops in one pathway.
Efeyan A, Sabatini DM. Efeyan A, et al. Curr Opin Cell Biol. 2010 Apr;22(2):169-76. doi: 10.1016/j.ceb.2009.10.007. Epub 2009 Nov 27. Curr Opin Cell Biol. 2010. PMID: 19945836 Free PMC article.
Amino acids and mTORC1: from lysosomes to disease.
Efeyan A, Zoncu R, Sabatini DM. Efeyan A, et al. Trends Mol Med. 2012 Sep;18(9):524-33. doi: 10.1016/j.molmed.2012.05.007. Epub 2012 Jun 28. Trends Mol Med. 2012. PMID: 22749019 Free PMC article. Review.
Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
de la Calle Arregui C, Plata-Gómez AB, Deleyto-Seldas N, García F, Ortega-Molina A, Abril-Garrido J, Rodriguez E, Nemazanyy I, Tribouillard L, de Martino A, Caleiras E, Campos-Olivas R, Mulero F, Laplante M, Muñoz J, Pende M, Sabio G, Sabatini DM, Efeyan A. de la Calle Arregui C, et al. Among authors: efeyan a. Nat Commun. 2021 Jun 16;12(1):3660. doi: 10.1038/s41467-021-23857-8. Nat Commun. 2021. PMID: 34135321 Free PMC article.
Nutrient-sensing mechanisms and pathways.
Efeyan A, Comb WC, Sabatini DM. Efeyan A, et al. Nature. 2015 Jan 15;517(7534):302-10. doi: 10.1038/nature14190. Nature. 2015. PMID: 25592535 Free PMC article. Review.
57 results