Radic Z - Search Results

1

The Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism.

Bourne Y, Sulzenbacher G, Chabaud L, Aráoz R, Radić Z, Conrod S, Taylor P, Guillou C, Molgó J, Marchot P. Bourne Y, et al. Among authors: radic z. Mar Drugs. 2024 Mar 27;22(4):149. doi: 10.3390/md22040149. Mar Drugs. 2024. PMID: 38667766 Free PMC article.

2

Connectivity between surface and interior in catalytic subunits of acetylcholinesterases inferred from their X-ray structures.

Radić Z. Radić Z. J Neurochem. 2024 Apr;168(4):386-396. doi: 10.1111/jnc.15802. Epub 2023 Mar 19. J Neurochem. 2024. PMID: 36892323 Review.

3

Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice.

Chang S, Tat J, China SP, Kalyanaraman H, Zhuang S, Chan A, Lai C, Radic Z, Abdel-Rahman EA, Casteel DE, Pilz RB, Ali SS, Boss GR. Chang S, et al. Among authors: radic z. PNAS Nexus. 2022 Sep 14;1(4):pgac191. doi: 10.1093/pnasnexus/pgac191. eCollection 2022 Sep. PNAS Nexus. 2022. PMID: 36276587 Free PMC article.

4

Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering.

Gerlits O, Fajer M, Cheng X, Blumenthal DK, Radić Z, Kovalevsky A. Gerlits O, et al. Among authors: radic z. Structure. 2022 Nov 3;30(11):1538-1549.e3. doi: 10.1016/j.str.2022.09.006. Epub 2022 Oct 19. Structure. 2022. PMID: 36265484 Free PMC article.

5

Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure.

Gerlits O, Blakeley MP, Keen DA, Radić Z, Kovalevsky A. Gerlits O, et al. Among authors: radic z. Curr Res Struct Biol. 2021 Sep 6;3:206-215. doi: 10.1016/j.crstbi.2021.08.003. eCollection 2021. Curr Res Struct Biol. 2021. PMID: 34541552 Free PMC article.

6

Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects.

Blumenthal DK, Cheng X, Fajer M, Ho KY, Rohrer J, Gerlits O, Taylor P, Juneja P, Kovalevsky A, Radić Z. Blumenthal DK, et al. Among authors: radic z. J Biol Chem. 2021 Sep;297(3):101007. doi: 10.1016/j.jbc.2021.101007. Epub 2021 Jul 27. J Biol Chem. 2021. PMID: 34324828 Free PMC article.

7

Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures.

Shyong YJ, Sepulveda Y, Garcia A, Samskey NM, Radic Z, Sit RK, Sharpless KB, Momper JD, Taylor P. Shyong YJ, et al. Among authors: radic z. J Pharmacol Exp Ther. 2021 Sep;378(3):315-321. doi: 10.1124/jpet.121.000715. Epub 2021 Jun 18. J Pharmacol Exp Ther. 2021. PMID: 34145064 Free PMC article.

8

Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical.

Taylor P, Shyong YJ, Samskey N, Ho KY, Radic' Z, Fenical W, Sharpless KB, Kovarik Z, Camacho-Hernandez GA. Taylor P, et al. Among authors: radic z. J Neurochem. 2021 Sep;158(6):1217-1222. doi: 10.1111/jnc.15335. Epub 2021 Mar 12. J Neurochem. 2021. PMID: 33638151 Free article. Review.

9

Correction: Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase.

Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radić Z. Gorecki L, et al. Among authors: radic z. J Biol Chem. 2020 May 8;295(19):6784. doi: 10.1074/jbc.AAC120.013785. J Biol Chem. 2020. PMID: 32385098 Free PMC article. No abstract available.

10

Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase.

Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radić Z. Gorecki L, et al. Among authors: radic z. J Biol Chem. 2020 Mar 27;295(13):4079-4092. doi: 10.1074/jbc.RA119.012400. Epub 2020 Feb 4. J Biol Chem. 2020. PMID: 32019865 Free PMC article.

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