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152 results

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Page 1
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.
Simonelli F, Maguire AM, Testa F, Pierce EA, Mingozzi F, Bennicelli JL, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond TM, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, McDonnell JW, High KA, Bennett J, Auricchio A. Simonelli F, et al. Among authors: redmond tm. Mol Ther. 2010 Mar;18(3):643-50. doi: 10.1038/mt.2009.277. Epub 2009 Dec 1. Mol Ther. 2010. PMID: 19953081 Free PMC article. Clinical Trial.
Safety and efficacy of gene transfer for Leber's congenital amaurosis.
Maguire AM, Simonelli F, Pierce EA, Pugh EN Jr, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Surace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, Sun J, Jacobs J, Dell'Osso L, Hertle R, Ma JX, Redmond TM, Zhu X, Hauck B, Zelenaia O, Shindler KS, Maguire MG, Wright JF, Volpe NJ, McDonnell JW, Auricchio A, High KA, Bennett J. Maguire AM, et al. Among authors: redmond tm. N Engl J Med. 2008 May 22;358(21):2240-8. doi: 10.1056/NEJMoa0802315. Epub 2008 Apr 27. N Engl J Med. 2008. PMID: 18441370 Free PMC article. Clinical Trial.
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.
Maguire AM, High KA, Auricchio A, Wright JF, Pierce EA, Testa F, Mingozzi F, Bennicelli JL, Ying GS, Rossi S, Fulton A, Marshall KA, Banfi S, Chung DC, Morgan JI, Hauck B, Zelenaia O, Zhu X, Raffini L, Coppieters F, De Baere E, Shindler KS, Volpe NJ, Surace EM, Acerra C, Lyubarsky A, Redmond TM, Stone E, Sun J, McDonnell JW, Leroy BP, Simonelli F, Bennett J. Maguire AM, et al. Among authors: redmond tm. Lancet. 2009 Nov 7;374(9701):1597-605. doi: 10.1016/S0140-6736(09)61836-5. Epub 2009 Oct 23. Lancet. 2009. PMID: 19854499 Free PMC article. Clinical Trial.
In utero gene therapy rescues vision in a murine model of congenital blindness.
Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A, Redmond TM, Tang W, Wei Z, Rex TS, Glover E, Maguire AM, Pugh EN Jr, Jacobson SG, Bennett J. Dejneka NS, et al. Among authors: redmond tm. Mol Ther. 2004 Feb;9(2):182-8. doi: 10.1016/j.ymthe.2003.11.013. Mol Ther. 2004. PMID: 14759802 Free article.
Assessment of rAAV-mediated gene therapy in the Rpe65-/- mouse.
Rakoczy PE, Lai CM, Yu MJ, Daniels DM, Brankov M, Rae BC, Stoddart CW, Barnett NL, Martin-Iverson MT, Redmond TM, Narfstrom K, Zhou X, Constable IJ. Rakoczy PE, et al. Among authors: redmond tm. Adv Exp Med Biol. 2003;533:431-8. doi: 10.1007/978-1-4615-0067-4_55. Adv Exp Med Biol. 2003. PMID: 15180295 No abstract available.
A History of the Classical Visual Cycle.
Wright CB, Redmond TM, Nickerson JM. Wright CB, et al. Among authors: redmond tm. Prog Mol Biol Transl Sci. 2015;134:433-48. doi: 10.1016/bs.pmbts.2015.06.009. Epub 2015 Jul 3. Prog Mol Biol Transl Sci. 2015. PMID: 26310169 Review.
152 results