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Page 1
Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors.
Venkatesan AM, Dehnhardt CM, Chen Z, Santos ED, Dos Santos O, Bursavich M, Gilbert AM, Ellingboe JW, Ayral-Kaloustian S, Khafizova G, Brooijmans N, Mallon R, Hollander I, Feldberg L, Lucas J, Yu K, Gibbons J, Abraham R, Mansour TS. Venkatesan AM, et al. Among authors: santos ed. Bioorg Med Chem Lett. 2010 Jan 15;20(2):653-6. doi: 10.1016/j.bmcl.2009.11.057. Epub 2009 Dec 1. Bioorg Med Chem Lett. 2010. PMID: 19954970
PKI-179: an orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor.
Venkatesan AM, Chen Z, dos Santos O, Dehnhardt C, Santos ED, Ayral-Kaloustian S, Mallon R, Hollander I, Feldberg L, Lucas J, Yu K, Chaudhary I, Mansour TS. Venkatesan AM, et al. Among authors: santos ed. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5869-73. doi: 10.1016/j.bmcl.2010.07.104. Epub 2010 Jul 30. Bioorg Med Chem Lett. 2010. PMID: 20797855
Antitumor efficacy of PKI-587, a highly potent dual PI3K/mTOR kinase inhibitor.
Mallon R, Feldberg LR, Lucas J, Chaudhary I, Dehnhardt C, Santos ED, Chen Z, dos Santos O, Ayral-Kaloustian S, Venkatesan A, Hollander I. Mallon R, et al. Among authors: santos ed. Clin Cancer Res. 2011 May 15;17(10):3193-203. doi: 10.1158/1078-0432.CCR-10-1694. Epub 2011 Feb 15. Clin Cancer Res. 2011. PMID: 21325073
Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates.
Levin JI, Chen JM, Cheung K, Cole D, Crago C, Santos ED, Du X, Khafizova G, MacEwan G, Niu C, Salaski EJ, Zask A, Cummons T, Sung A, Xu J, Zhang Y, Xu W, Ayral-Kaloustian S, Jin G, Cowling R, Barone D, Mohler KM, Black RA, Skotnicki JS. Levin JI, et al. Among authors: santos ed. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2799-803. doi: 10.1016/s0960-894x(03)00514-6. Bioorg Med Chem Lett. 2003. PMID: 12873518
Effect of mesenchymal stem cells on the host response in severe community-acquired pneumonia.
Reijnders TDY, Laterre PF, François B, Sánchez García M, van Engelen TSR, Sie D, Scicluna BP, Ostanin DV, Galinsky KJ, Butler JM, Lombardo E, van der Poll T; SEPCELL study group. Reijnders TDY, et al. Thorax. 2024 Oct 16;79(11):1086-1090. doi: 10.1136/thorax-2024-222026. Thorax. 2024. PMID: 39322407 Free PMC article. Clinical Trial.
119 results