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Page 1
A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.
Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W. Thanh GL, et al. Among authors: muldoon c. J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919. J Org Chem. 2010. PMID: 19961235
Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.
Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W. Abbenante G, et al. Among authors: muldoon c. J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777. J Med Chem. 2010. PMID: 20684600
Targeting the forgotten transglycosylases.
Halliday J, McKeveney D, Muldoon C, Rajaratnam P, Meutermans W. Halliday J, et al. Among authors: muldoon c. Biochem Pharmacol. 2006 Mar 30;71(7):957-67. doi: 10.1016/j.bcp.2005.10.030. Epub 2005 Nov 18. Biochem Pharmacol. 2006. PMID: 16298347 Review.
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA. Zuegg J, et al. Among authors: muldoon c. Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719. Nat Commun. 2015. PMID: 26194781 Free PMC article.
Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.
Gallardo-Godoy A, Muldoon C, Becker B, Elliott AG, Lash LH, Huang JX, Butler MS, Pelingon R, Kavanagh AM, Ramu S, Phetsang W, Blaskovich MA, Cooper MA. Gallardo-Godoy A, et al. Among authors: muldoon c. J Med Chem. 2016 Feb 11;59(3):1068-77. doi: 10.1021/acs.jmedchem.5b01593. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26734854 Free PMC article.
Structure-Function Studies of Polymyxin B Lipononapeptides.
Gallardo-Godoy A, Hansford KA, Muldoon C, Becker B, Elliott AG, Huang JX, Pelingon R, Butler MS, Blaskovich MAT, Cooper MA. Gallardo-Godoy A, et al. Among authors: muldoon c. Molecules. 2019 Feb 2;24(3):553. doi: 10.3390/molecules24030553. Molecules. 2019. PMID: 30717415 Free PMC article.
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.
Blaskovich MAT, Hansford KA, Butler MS, Ramu S, Kavanagh AM, Jarrad AM, Prasetyoputri A, Pitt ME, Huang JX, Lindahl F, Ziora ZM, Bradford T, Muldoon C, Rajaratnam P, Pelingon R, Edwards DJ, Zhang B, Amado M, Elliott AG, Zuegg J, Coin L, Woischnig AK, Khanna N, Breidenstein E, Stincone A, Mason C, Khan N, Cho HK, Karau MJ, Greenwood-Quaintance KE, Patel R, Wootton M, James ML, Hutton ML, Lyras D, Ogunniyi AD, Mahdi LK, Trott DJ, Wu X, Niles S, Lewis K, Smith JR, Barber KE, Yim J, Rice SA, Rybak MJ, Ishmael CR, Hori KR, Bernthal NM, Francis KP, Roberts JA, Paterson DL, Cooper MA. Blaskovich MAT, et al. Among authors: muldoon c. Sci Transl Med. 2022 Sep 14;14(662):eabj2381. doi: 10.1126/scitranslmed.abj2381. Epub 2022 Sep 14. Sci Transl Med. 2022. PMID: 36103517
Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.
Blaskovich MAT, Hansford KA, Gong Y, Butler MS, Muldoon C, Huang JX, Ramu S, Silva AB, Cheng M, Kavanagh AM, Ziora Z, Premraj R, Lindahl F, Bradford TA, Lee JC, Karoli T, Pelingon R, Edwards DJ, Amado M, Elliott AG, Phetsang W, Daud NH, Deecke JE, Sidjabat HE, Ramaologa S, Zuegg J, Betley JR, Beevers APG, Smith RAG, Roberts JA, Paterson DL, Cooper MA. Blaskovich MAT, et al. Among authors: muldoon c. Nat Commun. 2018 Jan 2;9(1):22. doi: 10.1038/s41467-017-02123-w. Nat Commun. 2018. PMID: 29295973 Free PMC article.
Colonic oncostatin M expression evaluated by immunohistochemistry and infliximab therapy outcome in corticosteroid-refractory acute severe ulcerative colitis.
O'Connell J, Doherty J, Buckley A, Cormican D, Dunne C, Hartery K, Larkin J, MacCarthy F, McCormick P, McKiernan S, Mehigan B, Muldoon C, Ryan C, O'Sullivan J, Kevans D. O'Connell J, et al. Among authors: muldoon c. Intest Res. 2022 Jul;20(3):381-385. doi: 10.5217/ir.2021.00073. Epub 2022 Mar 11. Intest Res. 2022. PMID: 35263959 Free PMC article. No abstract available.
85 results