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The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.
Hedvat M, Huszar D, Herrmann A, Gozgit JM, Schroeder A, Sheehy A, Buettner R, Proia D, Kowolik CM, Xin H, Armstrong B, Bebernitz G, Weng S, Wang L, Ye M, McEachern K, Chen H, Morosini D, Bell K, Alimzhanov M, Ioannidis S, McCoon P, Cao ZA, Yu H, Jove R, Zinda M. Hedvat M, et al. Among authors: buettner r. Cancer Cell. 2009 Dec 8;16(6):487-97. doi: 10.1016/j.ccr.2009.10.015. Cancer Cell. 2009. PMID: 19962667 Free PMC article.
Prostate adenocarcinoma: cellular and molecular abnormalities.
Mora LB, Buettner R, Ahmad N, Bassel Y, Jove R, Seigne JD. Mora LB, et al. Among authors: buettner r. Cancer Control. 2001 Nov-Dec;8(6):551-61. doi: 10.1177/107327480100800612. Cancer Control. 2001. PMID: 11807425 Free article. Review. No abstract available.
Stat3 regulates genes common to both wound healing and cancer.
Dauer DJ, Ferraro B, Song L, Yu B, Mora L, Buettner R, Enkemann S, Jove R, Haura EB. Dauer DJ, et al. Among authors: buettner r. Oncogene. 2005 May 12;24(21):3397-408. doi: 10.1038/sj.onc.1208469. Oncogene. 2005. PMID: 15735721
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells.
Nam S, Buettner R, Turkson J, Kim D, Cheng JQ, Muehlbeyer S, Hippe F, Vatter S, Merz KH, Eisenbrand G, Jove R. Nam S, et al. Among authors: buettner r. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5998-6003. doi: 10.1073/pnas.0409467102. Epub 2005 Apr 18. Proc Natl Acad Sci U S A. 2005. PMID: 15837920 Free PMC article.
434 results