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Validation and implementation of a liquid chromatography/tandem mass spectrometry assay for quantitation of the total and unbound RO4929097, a γ-secretase inhibitor targeting Notch signaling, in human plasma.
Wu J, Wiegand R, LoRusso P, Li J. Wu J, et al. Among authors: wiegand r. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jun 1;879(19):1537-43. doi: 10.1016/j.jchromb.2011.03.045. Epub 2011 Mar 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21497565 Free PMC article.
Simultaneous determination of 1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl) uracil (FAU) and 1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl) 5-methyluracil (FMAU) in human plasma by liquid chromatography/tandem mass spectrometry.
Wiegand R, Wu J, Shields AF, Lorusso P, Li J. Wiegand R, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Apr 1;891-892:64-70. doi: 10.1016/j.jchromb.2012.02.030. Epub 2012 Feb 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22410089 Free PMC article.
A stable isotope-labeled internal standard is essential for correcting for the interindividual variability in the recovery of lapatinib from cancer patient plasma in quantitative LC-MS/MS analysis.
Wu J, Wiegand R, LoRusso P, Li J. Wu J, et al. Among authors: wiegand r. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec 15;941:100-8. doi: 10.1016/j.jchromb.2013.10.011. Epub 2013 Oct 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 24189203 Free PMC article.
Quantitative analysis of intracellular nucleoside triphosphates and other polar metabolites using ion pair reversed-phase liquid chromatography coupled with tandem mass spectrometry.
Wu J, Zhang Y, Wiegand R, Wang J, Bepler G, Li J. Wu J, et al. Among authors: wiegand r. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 1;1006:167-178. doi: 10.1016/j.jchromb.2015.10.030. Epub 2015 Oct 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26551209 Free PMC article.
323 results