Ashida H - Search Results

1

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response.

Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C. Ashida H, et al. Nat Cell Biol. 2010 Jan;12(1):66-73; sup pp 1-9. doi: 10.1038/ncb2006. Epub 2009 Dec 13. Nat Cell Biol. 2010. PMID: 20010814 Free PMC article.

2

A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling.

Iwai H, Kim M, Yoshikawa Y, Ashida H, Ogawa M, Fujita Y, Muller D, Kirikae T, Jackson PK, Kotani S, Sasakawa C. Iwai H, et al. Among authors: ashida h. Cell. 2007 Aug 24;130(4):611-23. doi: 10.1016/j.cell.2007.06.043. Cell. 2007. PMID: 17719540 Free article.

3

Cell death and infection: a double-edged sword for host and pathogen survival.

Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, Sasakawa C. Ashida H, et al. J Cell Biol. 2011 Dec 12;195(6):931-42. doi: 10.1083/jcb.201108081. Epub 2011 Nov 28. J Cell Biol. 2011. PMID: 22123830 Free PMC article. Review.

4

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.

Sanada T, Kim M, Mimuro H, Suzuki M, Ogawa M, Oyama A, Ashida H, Kobayashi T, Koyama T, Nagai S, Shibata Y, Gohda J, Inoue J, Mizushima T, Sasakawa C. Sanada T, et al. Among authors: ashida h. Nature. 2012 Mar 11;483(7391):623-6. doi: 10.1038/nature10894. Nature. 2012. PMID: 22407319

5

Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells.

Ashida H, Nakano H, Sasakawa C. Ashida H, et al. PLoS Pathog. 2013;9(6):e1003409. doi: 10.1371/journal.ppat.1003409. Epub 2013 Jun 6. PLoS Pathog. 2013. PMID: 23754945 Free PMC article.

6

Exploitation of the host ubiquitin system by human bacterial pathogens.

Ashida H, Kim M, Sasakawa C. Ashida H, et al. Nat Rev Microbiol. 2014 Jun;12(6):399-413. doi: 10.1038/nrmicro3259. Epub 2014 May 7. Nat Rev Microbiol. 2014. PMID: 24801936 Review.

7

Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.

Suzuki S, Mimuro H, Kim M, Ogawa M, Ashida H, Toyotome T, Franchi L, Suzuki M, Sanada T, Suzuki T, Tsutsui H, Núñez G, Sasakawa C. Suzuki S, et al. Among authors: ashida h. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):E4254-63. doi: 10.1073/pnas.1324021111. Epub 2014 Sep 22. Proc Natl Acad Sci U S A. 2014. PMID: 25246571 Free PMC article.

8

Bacterial E3 ligase effectors exploit host ubiquitin systems.

Ashida H, Sasakawa C. Ashida H, et al. Curr Opin Microbiol. 2017 Feb;35:16-22. doi: 10.1016/j.mib.2016.11.001. Epub 2016 Nov 28. Curr Opin Microbiol. 2017. PMID: 27907841 Review.

9

Shigella chromosomal IpaH proteins are secreted via the type III secretion system and act as effectors.

Ashida H, Toyotome T, Nagai T, Sasakawa C. Ashida H, et al. Mol Microbiol. 2007 Feb;63(3):680-93. doi: 10.1111/j.1365-2958.2006.05547.x. Epub 2007 Jan 4. Mol Microbiol. 2007. PMID: 17214743 Free article.

10

The versatility of Shigella effectors.

Ogawa M, Handa Y, Ashida H, Suzuki M, Sasakawa C. Ogawa M, et al. Among authors: ashida h. Nat Rev Microbiol. 2008 Jan;6(1):11-6. doi: 10.1038/nrmicro1814. Nat Rev Microbiol. 2008. PMID: 18059288 Review.

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