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ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L. Markljung E, et al. Among authors: jiang l. PLoS Biol. 2009 Dec;7(12):e1000256. doi: 10.1371/journal.pbio.1000256. Epub 2009 Dec 15. PLoS Biol. 2009. PMID: 20016685 Free PMC article.
Whole-genome resequencing reveals loci under selection during chicken domestication.
Rubin CJ, Zody MC, Eriksson J, Meadows JR, Sherwood E, Webster MT, Jiang L, Ingman M, Sharpe T, Ka S, Hallböök F, Besnier F, Carlborg O, Bed'hom B, Tixier-Boichard M, Jensen P, Siegel P, Lindblad-Toh K, Andersson L. Rubin CJ, et al. Among authors: jiang l. Nature. 2010 Mar 25;464(7288):587-91. doi: 10.1038/nature08832. Epub 2010 Mar 10. Nature. 2010. PMID: 20220755
Identification of a melanocyte-specific, microphthalmia-associated transcription factor-dependent regulatory element in the intronic duplication causing hair greying and melanoma in horses.
Sundström E, Komisarczuk AZ, Jiang L, Golovko A, Navratilova P, Rinkwitz S, Becker TS, Andersson L. Sundström E, et al. Among authors: jiang l. Pigment Cell Melanoma Res. 2012 Jan;25(1):28-36. doi: 10.1111/j.1755-148X.2011.00902.x. Epub 2011 Sep 21. Pigment Cell Melanoma Res. 2012. PMID: 21883983
ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells.
Jiang L, Wallerman O, Younis S, Rubin CJ, Gilbert ER, Sundström E, Ghazal A, Zhang X, Wang L, Mikkelsen TS, Andersson G, Andersson L. Jiang L, et al. PLoS One. 2014 Apr 8;9(4):e94187. doi: 10.1371/journal.pone.0094187. eCollection 2014. PLoS One. 2014. PMID: 24714595 Free PMC article.
ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells.
Wang X, Jiang L, Wallerman O, Younis S, Yu Q, Klaesson A, Tengholm A, Welsh N, Andersson L. Wang X, et al. Among authors: jiang l. FASEB J. 2019 Jan;33(1):88-100. doi: 10.1096/fj.201600835R. Epub 2018 Jun 29. FASEB J. 2019. PMID: 29957057
We conclude that ZBED6 acts as a transcriptional regulator in MIN6 cells and that its activity suppresses insulin production, cell aggregation, and neuronal-like differentiation.-Wang, X., Jiang, L., Wallerman, O., Younis, S., Yu, Q., Klaesson, A., Tengholm, A., Wel …
We conclude that ZBED6 acts as a transcriptional regulator in MIN6 cells and that its activity suppresses insulin production, cell aggregati …
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