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Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection.
Pipeling MR, West EE, Osborne CM, Whitlock AB, Dropulic LK, Willett MH, Forman M, Valsamakis A, Orens JB, Moller DR, Lechtzin N, Migueles SA, Connors M, McDyer JF. Pipeling MR, et al. Among authors: west ee. J Immunol. 2008 Jul 1;181(1):546-56. doi: 10.4049/jimmunol.181.1.546. J Immunol. 2008. PMID: 18566421 Free PMC article.
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.
Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, Ferraro A, Walsh PR, Kavanagh D, Afzali B, Lavender P, Lachmann HJ, Kemper C. Arbore G, et al. Among authors: west ee. Nat Commun. 2018 Oct 10;9(1):4186. doi: 10.1038/s41467-018-06706-z. Nat Commun. 2018. PMID: 30305631 Free PMC article.
Effector CD8 T cells dedifferentiate into long-lived memory cells.
Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, Ahmed R. Youngblood B, et al. Among authors: west ee. Nature. 2017 Dec 21;552(7685):404-409. doi: 10.1038/nature25144. Epub 2017 Dec 13. Nature. 2017. PMID: 29236683 Free PMC article.
62 results