Horne EA - Search Results

1

Chronic microsensors for longitudinal, subsecond dopamine detection in behaving animals.

Clark JJ, Sandberg SG, Wanat MJ, Gan JO, Horne EA, Hart AS, Akers CA, Parker JG, Willuhn I, Martinez V, Evans SB, Stella N, Phillips PE. Clark JJ, et al. Among authors: horne ea. Nat Methods. 2010 Feb;7(2):126-9. doi: 10.1038/nmeth.1412. Epub 2009 Dec 27. Nat Methods. 2010. PMID: 20037591 Free PMC article.

2

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.

Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, Xu C, Möller T, Mackie K, Manzoni OJ, Cravatt BF, Stella N. Marrs WR, et al. Among authors: horne ea. Nat Neurosci. 2010 Aug;13(8):951-7. doi: 10.1038/nn.2601. Epub 2010 Jul 25. Nat Neurosci. 2010. PMID: 20657592 Free PMC article.

3

NIR-mbc94, a fluorescent ligand that binds to endogenous CB(2) receptors and is amenable to high-throughput screening.

Sexton M, Woodruff G, Horne EA, Lin YH, Muccioli GG, Bai M, Stern E, Bornhop DJ, Stella N. Sexton M, et al. Among authors: horne ea. Chem Biol. 2011 May 27;18(5):563-8. doi: 10.1016/j.chembiol.2011.02.016. Chem Biol. 2011. PMID: 21609837 Free PMC article.

4

Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons.

Marrs WR, Horne EA, Ortega-Gutierrez S, Cisneros JA, Xu C, Lin YH, Muccioli GG, Lopez-Rodriguez ML, Stella N. Marrs WR, et al. Among authors: horne ea. J Biol Chem. 2011 Aug 19;286(33):28723-28728. doi: 10.1074/jbc.M110.202853. Epub 2011 Jun 10. J Biol Chem. 2011. PMID: 21665953 Free PMC article.

5

Modified carbazoles destabilize microtubules and kill glioblastoma multiform cells.

Diaz P, Horne E, Xu C, Hamel E, Wagenbach M, Petrov RR, Uhlenbruck B, Haas B, Hothi P, Wordeman L, Gussio R, Stella N. Diaz P, et al. Eur J Med Chem. 2018 Nov 5;159:74-89. doi: 10.1016/j.ejmech.2018.09.026. Epub 2018 Sep 11. Eur J Med Chem. 2018. PMID: 30268825 Free PMC article.

6

Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models.

Horne EA, Coy J, Swinney K, Fung S, Cherry AE, Marrs WR, Naydenov AV, Lin YH, Sun X, Keene CD, Grouzmann E, Muchowski P, Bates GP, Mackie K, Stella N. Horne EA, et al. Eur J Neurosci. 2013 Feb;37(3):429-40. doi: 10.1111/ejn.12045. Epub 2012 Nov 21. Eur J Neurosci. 2013. PMID: 23167744 Free PMC article.

7

A brain-penetrant microtubule-targeting agent that disrupts hallmarks of glioma tumorigenesis.

Horne EA, Diaz P, Cimino PJ, Jung E, Xu C, Hamel E, Wagenbach M, Kumasaka D, Wageling NB, Azorín DD, Winkler F, Wordeman LG, Holland EC, Stella N. Horne EA, et al. Neurooncol Adv. 2020 Dec 3;3(1):vdaa165. doi: 10.1093/noajnl/vdaa165. eCollection 2021 Jan-Dec. Neurooncol Adv. 2020. PMID: 33506204 Free PMC article.

8

ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice.

Naydenov AV, Horne EA, Cheah CS, Swinney K, Hsu KL, Cao JK, Marrs W, Blankman JL, Tu S, Cherry AE, Fung S, Wen A, Li W, Saporito MS, Selley DE, Cravatt BF, Oakley JC, Stella N. Naydenov AV, et al. Among authors: horne ea. Neuron. 2014 Jul 16;83(2):361-371. doi: 10.1016/j.neuron.2014.06.030. Neuron. 2014. PMID: 25033180 Free PMC article.

9

ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme.

Cherry AE, Haas BR, Naydenov AV, Fung S, Xu C, Swinney K, Wagenbach M, Freeling J, Canton DA, Coy J, Horne EA, Rickman B, Vicente JJ, Scott JD, Ho RJ, Liggitt D, Wordeman L, Stella N. Cherry AE, et al. Among authors: horne ea. Mol Cancer Ther. 2016 Sep;15(9):2018-29. doi: 10.1158/1535-7163.MCT-15-0800. Epub 2016 Jun 20. Mol Cancer Ther. 2016. PMID: 27325686 Free PMC article.

10

Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.

Lerner TN, Horne EA, Stella N, Kreitzer AC. Lerner TN, et al. Among authors: horne ea. J Neurosci. 2010 Feb 10;30(6):2160-4. doi: 10.1523/JNEUROSCI.5844-09.2010. J Neurosci. 2010. PMID: 20147543 Free PMC article.

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