Ghosh B - Search Results

1

Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.

Ghosh B, Antonio T, Zhen J, Kharkar P, Reith ME, Dutta AK. Ghosh B, et al. J Med Chem. 2010 Feb 11;53(3):1023-37. doi: 10.1021/jm901184n. J Med Chem. 2010. PMID: 20038106 Free PMC article.

2

Synthesis, screening and quantitative structure-activity relationship (QSAR) studies of some glutamine analogues for possible anticancer activity.

Srikanth K, Kumar ChA, Ghosh B, Jha T. Srikanth K, et al. Among authors: ghosh b. Bioorg Med Chem. 2002 Jul;10(7):2119-31. doi: 10.1016/s0968-0896(02)00079-2. Bioorg Med Chem. 2002. PMID: 11983508

3

Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration of action.

Biswas S, Zhang S, Fernandez F, Ghosh B, Zhen J, Kuzhikandathil E, Reith ME, Dutta AK. Biswas S, et al. Among authors: ghosh b. J Med Chem. 2008 Jan 10;51(1):101-17. doi: 10.1021/jm070860r. Epub 2007 Dec 12. J Med Chem. 2008. PMID: 18072730

4

Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity.

Biswas S, Hazeldine S, Ghosh B, Parrington I, Kuzhikandathil E, Reith ME, Dutta AK. Biswas S, et al. Among authors: ghosh b. J Med Chem. 2008 May 22;51(10):3005-19. doi: 10.1021/jm701524h. Epub 2008 Apr 12. J Med Chem. 2008. PMID: 18410082

5

D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.

Dutta AK, Ghosh B, Biswas S, Reith ME. Dutta AK, et al. Among authors: ghosh b. Eur J Pharmacol. 2008 Jul 28;589(1-3):73-9. doi: 10.1016/j.ejphar.2008.05.008. Epub 2008 May 20. Eur J Pharmacol. 2008. PMID: 18561912

6

Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and its analogues as highly potent dopamine D2/D3 agonists and as iron chelator: in vivo activity indicates potential application in symptomatic and neuroprotective therapy for Parkinson's disease.

Ghosh B, Antonio T, Reith ME, Dutta AK. Ghosh B, et al. J Med Chem. 2010 Mar 11;53(5):2114-25. doi: 10.1021/jm901618d. J Med Chem. 2010. PMID: 20146482 Free PMC article.

7

Further delineation of hydrophobic binding sites in dopamine D(2)/D(3) receptors for N-4 substituents on the piperazine ring of the hybrid template 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol.

Ghosh B, Antonio T, Gopishetty B, Reith M, Dutta A. Ghosh B, et al. Bioorg Med Chem. 2010 Aug 1;18(15):5661-74. doi: 10.1016/j.bmc.2010.06.025. Epub 2010 Jun 12. Bioorg Med Chem. 2010. PMID: 20605099 Free PMC article.

8

Discovery of Novel 2-Amino-5-(Substituted)-1,3,4-Thiadiazole Derivatives: New Utilities for Colon Cancer Treatment.

Raj V, Rai A, Singh AK, Keshari AK, Trivedi P, Ghosh B, Kumar U, Kumar D, Saha S. Raj V, et al. Among authors: ghosh b. Anticancer Agents Med Chem. 2018;18(5):719-738. doi: 10.2174/1871520617666170419122916. Anticancer Agents Med Chem. 2018. PMID: 28425852

9

Quantitative structure-activity relationship study using refractotopological state atom index on some neonicotinoid insecticides.

Debnath B, Gayen S, Basu A, Ghosh B, Srikanth K, Jha T. Debnath B, et al. Among authors: ghosh b. Bioorg Med Chem. 2004 Dec 1;12(23):6137-45. doi: 10.1016/j.bmc.2004.09.003. Bioorg Med Chem. 2004. PMID: 15519158

10

Novel natural product-based cinnamates and their thio and thiono analogs as potent inhibitors of cell adhesion molecules on human endothelial cells.

Kumar S, Singh BK, Arya P, Malhotra S, Thimmulappa R, Prasad AK, Van der Eycken E, Olsen CE, DePass AL, Biswal S, Parmar VS, Ghosh B. Kumar S, et al. Among authors: ghosh b. Eur J Med Chem. 2011 Nov;46(11):5498-511. doi: 10.1016/j.ejmech.2011.09.008. Epub 2011 Sep 16. Eur J Med Chem. 2011. PMID: 21955679

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