El-Deiry WS - Search Results

1

Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma.

Katz SI, Zhou L, Chao G, Smith CD, Ferrara T, Wang W, Dicker DT, El-Deiry WS. Katz SI, et al. Cancer Biol Ther. 2009 Dec;8(24):2406-16. doi: 10.4161/cbt.8.24.10824. Epub 2009 Dec 2. Cancer Biol Ther. 2009. PMID: 20038816 Free PMC article.

2

Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death.

Blagosklonny MV, Giannakakou P, el-Deiry WS, Kingston DG, Higgs PI, Neckers L, Fojo T. Blagosklonny MV, et al. Cancer Res. 1997 Jan 1;57(1):130-5. Cancer Res. 1997. PMID: 8988053

3

p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4.

Xu SQ, El-Deiry WS. Xu SQ, et al. Biochem Biophys Res Commun. 2000 Mar 5;269(1):179-90. doi: 10.1006/bbrc.2000.2247. Biochem Biophys Res Commun. 2000. PMID: 10694497

4

Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance.

Ozören N, Fisher MJ, Kim K, Liu CX, Genin A, Shifman Y, Dicker DT, Spinner NB, Lisitsyn NA, El-Deiry WS. Ozören N, et al. Int J Oncol. 2000 May;16(5):917-25. doi: 10.3892/ijo.16.5.917. Int J Oncol. 2000. PMID: 10762627

5

KILLER/DR5, a novel DNA-damage inducible death receptor gene, links the p53-tumor suppressor to caspase activation and apoptotic death.

Wu GS, Kim K, el-Deiry WS. Wu GS, et al. Adv Exp Med Biol. 2000;465:143-51. doi: 10.1007/0-306-46817-4_13. Adv Exp Med Biol. 2000. PMID: 10810622 Review.

6

Repression of BRCA1 through a feedback loop involving p53.

MacLachlan TK, Dash BC, Dicker DT, El-Deiry WS. MacLachlan TK, et al. J Biol Chem. 2000 Oct 13;275(41):31869-75. doi: 10.1074/jbc.M003338200. J Biol Chem. 2000. PMID: 10884389 Free article.

7

The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.

Ozoren N, Kim K, Burns TF, Dicker DT, Moscioni AD, El-Deiry WS. Ozoren N, et al. Cancer Res. 2000 Nov 15;60(22):6259-65. Cancer Res. 2000. PMID: 11103780

8

Bax is a transcriptional target and mediator of c-myc-induced apoptosis.

Mitchell KO, Ricci MS, Miyashita T, Dicker DT, Jin Z, Reed JC, El-Deiry WS. Mitchell KO, et al. Cancer Res. 2000 Nov 15;60(22):6318-25. Cancer Res. 2000. PMID: 11103792

9

Enhanced TRAIL sensitivity by p53 overexpression in human cancer but not normal cell lines.

Kim K, Takimoto R, Dicker DT, Chen Y, Gazitt Y, El-Deiry WS. Kim K, et al. Int J Oncol. 2001 Feb;18(2):241-7. doi: 10.3892/ijo.18.2.241. Int J Oncol. 2001. PMID: 11172588

10

Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling.

McDonald ER 3rd, Chui PC, Martelli PF, Dicker DT, El-Deiry WS. McDonald ER 3rd, et al. J Biol Chem. 2001 May 4;276(18):14939-45. doi: 10.1074/jbc.M100399200. Epub 2001 Feb 13. J Biol Chem. 2001. PMID: 11279061 Free article.

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