Gaynor JW - Search Results

1

A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3'-5' and 5'-3' strands by rotating a single active site.

Sasnauskas G, Zakrys L, Zaremba M, Cosstick R, Gaynor JW, Halford SE, Siksnys V. Sasnauskas G, et al. Among authors: gaynor jw. Nucleic Acids Res. 2010 Apr;38(7):2399-410. doi: 10.1093/nar/gkp1194. Epub 2010 Jan 4. Nucleic Acids Res. 2010. PMID: 20047964 Free PMC article.

2

Incorporation of 3'-S-phosphorothiolates into RNA: potential applications in RNAi.

Gaynor J, Fisher J, Campbell B, Cosstick R. Gaynor J, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):319-20. doi: 10.1093/nass/nrn161. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776382

3

Dinucleotides containing 3'-S-phosphorothiolate linkages.

Gaynor JW, Cosstick R. Gaynor JW, et al. Methods Mol Biol. 2011;764:17-30. doi: 10.1007/978-1-61779-188-8_2. Methods Mol Biol. 2011. PMID: 21748631

4

RNA interference: a chemist's perspective.

Gaynor JW, Campbell BJ, Cosstick R. Gaynor JW, et al. Chem Soc Rev. 2010 Nov;39(11):4169-84. doi: 10.1039/b920362c. Epub 2010 Aug 17. Chem Soc Rev. 2010. PMID: 20717561 Review.

5

Thermal stabilisation of RNA·RNA duplexes and G-quadruplexes by phosphorothiolate linkages.

Piperakis MM, Gaynor JW, Fisher J, Cosstick R. Piperakis MM, et al. Among authors: gaynor jw. Org Biomol Chem. 2013 Feb 14;11(6):966-74. doi: 10.1039/c2ob26940f. Epub 2012 Dec 19. Org Biomol Chem. 2013. PMID: 23250349

6

Synthesis of the 3'-thio-nucleosides and subsequent automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage.

Gaynor JW, Bentley J, Cosstick R. Gaynor JW, et al. Nat Protoc. 2007;2(12):3122-35. doi: 10.1038/nprot.2007.451. Nat Protoc. 2007. PMID: 18079712

7

Reverse-direction (5'-->3') synthesis of oligonucleotides containing a 3'-S-phosphorothiolate linkage and 3'-terminal 3'-thionucleosides.

Gaynor JW, Piperakis MM, Fisher J, Cosstick R. Gaynor JW, et al. Org Biomol Chem. 2010 Mar 21;8(6):1463-70. doi: 10.1039/b923545k. Epub 2010 Jan 28. Org Biomol Chem. 2010. PMID: 20204222

8

Synthesis of 3'- S-phosphorothiolate oligonucleotides for their potential use in RNA interference.

Gaynor JW, Brazier J, Cosstick R. Gaynor JW, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):709-12. doi: 10.1080/15257770701490753. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066885

9

Invited commentary.

Gaynor JW, Wernovsky G, Clancy R. Gaynor JW, et al. Ann Thorac Surg. 2006 Mar;81(3):967. doi: 10.1016/j.athoracsur.2005.10.018. Ann Thorac Surg. 2006. PMID: 16488702 No abstract available.

10

Management of sinus venosus defects.

Gaynor JW. Gaynor JW. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006:35-9. doi: 10.1053/j.pcsu.2006.02.008. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006. PMID: 16638545

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