Hyun YL - Search Results

1

Design, synthesis, and evaluation of 2-aryl-7-(3',4'-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines as novel PDE-4 inhibitors.

Kim I, Song JH, Park CM, Jeong JW, Kim HR, Ha JR, No Z, Hyun YL, Cho YS, Sook Kang N, Jeon DJ. Kim I, et al. Among authors: hyun yl. Bioorg Med Chem Lett. 2010 Feb 1;20(3):922-6. doi: 10.1016/j.bmcl.2009.12.070. Epub 2009 Dec 23. Bioorg Med Chem Lett. 2010. PMID: 20053559

2

Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta.

Shin D, Lee SC, Heo YS, Lee WY, Cho YS, Kim YE, Hyun YL, Cho JM, Lee YS, Ro S. Shin D, et al. Among authors: hyun yl. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5686-9. doi: 10.1016/j.bmcl.2007.07.056. Epub 2007 Aug 19. Bioorg Med Chem Lett. 2007. PMID: 17764934

3

Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules.

Sung BJ, Hwang KY, Jeon YH, Lee JI, Heo YS, Kim JH, Moon J, Yoon JM, Hyun YL, Kim E, Eum SJ, Park SY, Lee JO, Lee TG, Ro S, Cho JM. Sung BJ, et al. Among authors: hyun yl. Nature. 2003 Sep 4;425(6953):98-102. doi: 10.1038/nature01914. Nature. 2003. PMID: 12955149

4

Structural chemoproteomics and drug discovery.

Shin D, Heo YS, Lee KJ, Kim CM, Yoon JM, Lee JI, Hyun YL, Jeon YH, Lee TG, Cho JM, Ro S. Shin D, et al. Among authors: hyun yl. Biopolymers. 2005;80(2-3):258-63. doi: 10.1002/bip.20263. Biopolymers. 2005. PMID: 15812788

5

Novel histone deacetylase inhibitors CG05 and CG06 effectively reactivate latently infected HIV-1.

Choi BS, Lee HS, Oh YT, Hyun YL, Ro S, Kim SS, Hong KJ. Choi BS, et al. Among authors: hyun yl. AIDS. 2010 Feb 20;24(4):609-11. doi: 10.1097/QAD.0b013e328333bfa1. AIDS. 2010. PMID: 20154582

6

A novel histone deacetylase inhibitor, CG0006, induces cell death through both extrinsic and intrinsic apoptotic pathways.

Hwang JJ, Kim YS, Kim MJ, Jang S, Lee JH, Choi J, Ro S, Hyun YL, Lee JS, Kim CS. Hwang JJ, et al. Among authors: hyun yl. Anticancer Drugs. 2009 Oct;20(9):815-21. doi: 10.1097/CAD.0b013e3283300a0f. Anticancer Drugs. 2009. PMID: 19644355

7

Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

Heo YS, Kim SK, Seo CI, Kim YK, Sung BJ, Lee HS, Lee JI, Park SY, Kim JH, Hwang KY, Hyun YL, Jeon YH, Ro S, Cho JM, Lee TG, Yang CH. Heo YS, et al. Among authors: hyun yl. EMBO J. 2004 Jun 2;23(11):2185-95. doi: 10.1038/sj.emboj.7600212. Epub 2004 May 13. EMBO J. 2004. PMID: 15141161 Free PMC article.

8

Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.

Cho YS, Lee JI, Shin D, Kim HT, Cheon YH, Seo CI, Kim YE, Hyun YL, Lee YS, Sugiyama K, Park SY, Ro S, Cho JM, Lee TG, Heo YS. Cho YS, et al. Among authors: hyun yl. Proteins. 2008 Jan 1;70(1):268-72. doi: 10.1002/prot.21611. Proteins. 2008. PMID: 17876819 No abstract available.

9

CG0006, a novel histone deacetylase inhibitor, induces breast cancer cell death via histone-acetylation and chaperone-disrupting pathways independent of ER status.

Kim HM, Kim CS, Lee JH, Jang SJ, Hwang JJ, Ro S, Hyun YL, Choi J. Kim HM, et al. Among authors: hyun yl. Breast Cancer Res Treat. 2011 Nov;130(2):365-75. doi: 10.1007/s10549-010-1310-4. Epub 2010 Dec 24. Breast Cancer Res Treat. 2011. PMID: 21184271

10

In vitro chemosensitivity of gastric adenocarcinomas to histone deacetylase inhibitors, compared to established drugs.

Yoon SN, Roh SA, Cho DH, Kim MB, Hyun YL, Ro S, Kim BS, Kim SY, Kim YS, Kim JC. Yoon SN, et al. Among authors: hyun yl. Hepatogastroenterology. 2010 May-Jun;57(99-100):657-62. Hepatogastroenterology. 2010. PMID: 20698245

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